• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Management of breast cancer by vaccine: fact or fiction.通过疫苗治疗乳腺癌:事实还是虚构
J IMA. 2013 Apr 22;44(1). doi: 10.5915/44-1-9055. Print 2012.
2
Breast Cancer Vaccines: New Insights.乳腺癌疫苗:新见解
Front Endocrinol (Lausanne). 2017 Oct 13;8:270. doi: 10.3389/fendo.2017.00270. eCollection 2017.
3
Breast cancer under age 40: a different approach.40岁以下乳腺癌:一种不同的治疗方法。
Curr Treat Options Oncol. 2015 Apr;16(4):16. doi: 10.1007/s11864-015-0334-8.
4
Management of breast cancer after Hodgkin's lymphoma and paediatric cancer.霍奇金淋巴瘤和儿科癌症治疗后的乳腺癌管理。
Eur J Cancer. 2015 Sep;51(13):1667-74. doi: 10.1016/j.ejca.2015.05.024. Epub 2015 Jun 16.
5
FERTILITY PRESERVATION IN YOUNG WOMEN WITH EARLY-STAGE BREAST CANCER.早期乳腺癌年轻女性的生育力保存
Acta Clin Croat. 2019 Mar;58(1):147-156. doi: 10.20471/acc.2019.58.01.19.
6
Optimal Management of Leptomeningeal Carcinomatosis in Breast Cancer Patients-A Systematic Review.乳腺癌患者软脑膜癌病的最佳管理——一项系统评价
Clin Breast Cancer. 2016 Dec;16(6):456-470. doi: 10.1016/j.clbc.2016.07.014. Epub 2016 Jul 28.
7
Recent Progress on Immunotherapy for Breast Cancer: Tumor Microenvironment, Nanotechnology and More.乳腺癌免疫治疗的最新进展:肿瘤微环境、纳米技术及其他
Front Bioeng Biotechnol. 2021 Jun 2;9:680315. doi: 10.3389/fbioe.2021.680315. eCollection 2021.
8
Enhancing Endocrine Therapy Combination Strategies for the Treatment of Postmenopausal HR+/HER2- Advanced Breast Cancer.强化内分泌治疗联合策略用于治疗绝经后激素受体阳性/人表皮生长因子受体2阴性晚期乳腺癌
Oncologist. 2017 Jan;22(1):12-24. doi: 10.1634/theoncologist.2016-0185. Epub 2016 Nov 18.
9
Optimal management of breast cancer in the elderly patient: current perspectives.老年乳腺癌患者的优化管理:当前观点
Clin Interv Aging. 2015 Jan 6;10:157-74. doi: 10.2147/CIA.S50670. eCollection 2015.
10
The Emerging Role of MicroRNAs in Breast Cancer.微小RNA在乳腺癌中的新兴作用
J Oncol. 2020 Jul 3;2020:9160905. doi: 10.1155/2020/9160905. eCollection 2020.

本文引用的文献

1
An autoimmune-mediated strategy for prophylactic breast cancer vaccination.一种用于预防性乳腺癌疫苗接种的自身免疫介导策略。
Nat Med. 2010 Jul;16(7):799-803. doi: 10.1038/nm.2161. Epub 2010 May 30.
2
MUC1-based recombinant Bacillus Calmette-Guerin vaccines as candidates for breast cancer immunotherapy.基于 MUC1 的重组卡介苗疫苗作为乳腺癌免疫治疗的候选物。
Expert Opin Biol Ther. 2010 Jul;10(7):1037-48. doi: 10.1517/14712598.2010.485185.
3
Immunization with two recombinant Bacillus Calmette-Guérin vaccines that combine the expression of multiple tandem repeats of mucin-1 and colony stimulating-factor suppress breast tumor growth in mice.用两种重组卡介苗疫苗进行免疫接种,这两种疫苗结合了粘蛋白-1多个串联重复序列的表达和集落刺激因子,可抑制小鼠乳腺肿瘤生长。
J Cancer Res Clin Oncol. 2010 Sep;136(9):1359-67. doi: 10.1007/s00432-010-0787-x. Epub 2010 Feb 3.
4
MUC1 based breast cancer vaccines: role of post translational modifications.基于MUC1的乳腺癌疫苗:翻译后修饰的作用
J Ayub Med Coll Abbottabad. 2008 Oct-Dec;20(4):130-3.
5
An essential epitope of anti-MUC1 monoclonal antibody KL-6 revealed by focused glycopeptide library.通过聚焦糖肽文库揭示抗 MUC1 单克隆抗体 KL-6 的一个必需表位。
J Am Chem Soc. 2009 Dec 2;131(47):17102-9. doi: 10.1021/ja903361f.
6
A novel Bacillus Calmette-Guérin-based breast cancer vaccine that coexpresses multiple tandem repeats of MUC1 and CD80 breaks the immune tolerance and inhibits MUC1-positive breast cancer growth.一种新型的基于卡介苗的乳腺癌疫苗,可共表达多个串联重复的 MUC1 和 CD80,打破了免疫耐受,并抑制了 MUC1 阳性乳腺癌的生长。
Cancer Biother Radiopharm. 2009 Oct;24(5):607-13. doi: 10.1089/cbr.2009.0622.
7
The Tat-conjugated N-terminal region of mucin antigen 1 (MUC1) induces protective immunity against MUC1-expressing tumours.黏蛋白抗原1(MUC1)的Tat缀合N端区域可诱导针对表达MUC1的肿瘤的保护性免疫。
Clin Exp Immunol. 2009 Nov;158(2):174-85. doi: 10.1111/j.1365-2249.2009.03997.x. Epub 2009 Jul 17.
8
Targeted delivery of tumor antigens to activated dendritic cells via CD11c molecules induces potent antitumor immunity in mice.通过CD11c分子将肿瘤抗原靶向递送至活化的树突状细胞可在小鼠中诱导强大的抗肿瘤免疫。
Clin Cancer Res. 2009 Jul 15;15(14):4612-21. doi: 10.1158/1078-0432.CCR-08-3321. Epub 2009 Jul 7.
9
Pilot study of vaccination with recombinant CEA-MUC-1-TRICOM poxviral-based vaccines in patients with metastatic carcinoma.重组CEA-MUC-1-TRICOM痘病毒疫苗接种治疗转移性癌患者的初步研究。
Clin Cancer Res. 2008 May 15;14(10):3060-9. doi: 10.1158/1078-0432.CCR-08-0126.
10
Optimized DNA vaccines to specifically induce therapeutic CD8 T cell responses against autochthonous breast tumors.优化的DNA疫苗可特异性诱导针对原发性乳腺肿瘤的治疗性CD8 T细胞反应。
Cancer Immunol Immunother. 2008 Nov;57(11):1695-703. doi: 10.1007/s00262-008-0465-x. Epub 2008 Feb 6.

通过疫苗治疗乳腺癌:事实还是虚构

Management of breast cancer by vaccine: fact or fiction.

作者信息

Das Soumen, Paul Retina, De Utpal, Mukherjee Mrityunjay

机构信息

Institute of Post Graduate Medical Education & Research and Seth Sukhlal Karnani Memorial Hospital Kolkata, West Bengal, India.

出版信息

J IMA. 2013 Apr 22;44(1). doi: 10.5915/44-1-9055. Print 2012.

DOI:10.5915/44-1-9055
PMID:23864997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3708638/
Abstract

Breast cancer (BC) is the most common malignancy (75-80%) among women. Options for management of BC are multivariate. Available modalities include surgery, radiotherapy, chemotherapy and hormone therapy. Despite availability of improved therapeutic adjuncts, mortality from BC is 40%. Vaccination strategies against BC are emerging as a viable alternative. This review highlights the available results of this emerging therapeutic strategy.

摘要

乳腺癌(BC)是女性中最常见的恶性肿瘤(占75 - 80%)。乳腺癌的治疗方案是多方面的。现有的治疗方式包括手术、放疗、化疗和激素治疗。尽管有了改进的治疗辅助手段,但乳腺癌的死亡率仍为40%。针对乳腺癌的疫苗接种策略正成为一种可行的替代方案。本综述重点介绍了这种新兴治疗策略的现有成果。