Saguem M H, Widgren S
Département de Pathologie, Centre Médical Universitaire, Genève, Suisse.
Ann Pathol. 1990;10(3):187-90.
A 78 year old male patient who had been treated by haemodialysis for 17 years for renal failure, secondary to tuberculosis, is reported. Following severe rectal bleeding, an ischaemic ulcer of the ascending colon was noticed, which required right hemicolectomy. On the surgical specimen, the ulcer showed massive vascular involvement with amyloidosis of the type found in haemodialysed patients, and constituted of beta 2 micro-globulin deposits. These amyloid deposits have certainly played an important part in the development of this ischaemic lesion.
报道了一名78岁男性患者,因肾衰竭接受血液透析治疗17年,肾衰竭继发于结核病。在严重直肠出血后,发现升结肠有缺血性溃疡,需要进行右半结肠切除术。在手术标本上,溃疡显示有大量血管受累,伴有血液透析患者中发现的那种淀粉样变性,由β2微球蛋白沉积物构成。这些淀粉样沉积物肯定在这种缺血性病变的发展中起了重要作用。