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使用带有硼中子吸收体的眼部探头进行质子眼部治疗的次级中子剂量测量。

Secondary neutron dose measurement for proton eye treatment using an eye snout with a borated neutron absorber.

机构信息

Department of Radiation Oncology, Kyung Hee University Hospital at Gandong, Seoul, Korea.

出版信息

Radiat Oncol. 2013 Jul 17;8:182. doi: 10.1186/1748-717X-8-182.

Abstract

BACKGROUND

We measured and assessed ways to reduce the secondary neutron dose from a system for proton eye treatment.

METHODS

Proton beams of 60.30 MeV were delivered through an eye-treatment snout in passive scattering mode. Allyl diglycol carbonate (CR-39) etch detectors were used to measure the neutron dose in the external field at 0.00, 1.64, and 6.00 cm depths in a water phantom. Secondary neutron doses were measured and compared between those with and without a high-hydrogen-boron-containing block. In addition, the neutron energy and vertices distribution were obtained by using a Geant4 Monte Carlo simulation.

RESULTS

The ratio of the maximum neutron dose equivalent to the proton absorbed dose (H(10)/D) at 2.00 cm from the beam field edge was 8.79 ± 1.28 mSv/Gy. The ratio of the neutron dose equivalent to the proton absorbed dose with and without a high hydrogen-boron containing block was 0.63 ± 0.06 to 1.15 ± 0.13 mSv/Gy at 2.00 cm from the edge of the field at depths of 0.00, 1.64, and 6.00 cm.

CONCLUSIONS

We found that the out-of-field secondary neutron dose in proton eye treatment with an eye snout is relatively small, and it can be further reduced by installing a borated neutron absorbing material.

摘要

背景

我们测量和评估了降低质子眼部治疗系统中次级中子剂量的方法。

方法

采用被动散射模式,用 60.30 MeV 的质子束通过眼部治疗探头传输。使用丙烯基二甘醇碳酸酯(CR-39)蚀刻探测器在水模体中测量 0.00、1.64 和 6.00 cm 深度处外部场中的中子剂量。比较了有和没有高含氢硼块的情况下的次级中子剂量。此外,还通过 Geant4 蒙特卡罗模拟获得了中子能量和顶点分布。

结果

距束场边缘 2.00 cm 处最大中子剂量当量与质子吸收剂量(H(10)/D)的比值为 8.79±1.28 mSv/Gy。距场边缘 2.00 cm 处 0.00、1.64 和 6.00 cm 深度处,有和没有高含氢硼块的情况下,中子剂量当量与质子吸收剂量的比值分别为 0.63±0.06 至 1.15±0.13 mSv/Gy。

结论

我们发现,眼部探头质子眼部治疗的场外次级中子剂量相对较小,通过安装硼中子吸收材料可以进一步降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6185/3723544/5e9f3c39a785/1748-717X-8-182-1.jpg

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