Department of Radiation Oncology, Kyung Hee University Hospital at Gandong, Seoul, Korea.
Radiat Oncol. 2013 Jul 17;8:182. doi: 10.1186/1748-717X-8-182.
We measured and assessed ways to reduce the secondary neutron dose from a system for proton eye treatment.
Proton beams of 60.30 MeV were delivered through an eye-treatment snout in passive scattering mode. Allyl diglycol carbonate (CR-39) etch detectors were used to measure the neutron dose in the external field at 0.00, 1.64, and 6.00 cm depths in a water phantom. Secondary neutron doses were measured and compared between those with and without a high-hydrogen-boron-containing block. In addition, the neutron energy and vertices distribution were obtained by using a Geant4 Monte Carlo simulation.
The ratio of the maximum neutron dose equivalent to the proton absorbed dose (H(10)/D) at 2.00 cm from the beam field edge was 8.79 ± 1.28 mSv/Gy. The ratio of the neutron dose equivalent to the proton absorbed dose with and without a high hydrogen-boron containing block was 0.63 ± 0.06 to 1.15 ± 0.13 mSv/Gy at 2.00 cm from the edge of the field at depths of 0.00, 1.64, and 6.00 cm.
We found that the out-of-field secondary neutron dose in proton eye treatment with an eye snout is relatively small, and it can be further reduced by installing a borated neutron absorbing material.
我们测量和评估了降低质子眼部治疗系统中次级中子剂量的方法。
采用被动散射模式,用 60.30 MeV 的质子束通过眼部治疗探头传输。使用丙烯基二甘醇碳酸酯(CR-39)蚀刻探测器在水模体中测量 0.00、1.64 和 6.00 cm 深度处外部场中的中子剂量。比较了有和没有高含氢硼块的情况下的次级中子剂量。此外,还通过 Geant4 蒙特卡罗模拟获得了中子能量和顶点分布。
距束场边缘 2.00 cm 处最大中子剂量当量与质子吸收剂量(H(10)/D)的比值为 8.79±1.28 mSv/Gy。距场边缘 2.00 cm 处 0.00、1.64 和 6.00 cm 深度处,有和没有高含氢硼块的情况下,中子剂量当量与质子吸收剂量的比值分别为 0.63±0.06 至 1.15±0.13 mSv/Gy。
我们发现,眼部探头质子眼部治疗的场外次级中子剂量相对较小,通过安装硼中子吸收材料可以进一步降低。