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腹部结核:233例的流行病学概况及治疗经验

Abdominal tuberculosis: epidemiologic profile and management experience of 233 cases.

作者信息

Saaiq Muhammad, Shah Syed Aslam, Zubair Muhammad

机构信息

Department of General Surgery, Pakistan Institute of Medical Sciences (PIMS), Islamabad.

出版信息

J Pak Med Assoc. 2012 Jul;62(7):704-7.

Abstract

OBJECTIVE

To document the epidemiologic profile and management outcome of patients with abdominal tuberculosis in a tertiary care setup.

METHODS

This descriptive case series was conducted at the Department of Surgery, Pakistan Institute of Medical Sciences (PIMS), Islamabad, between January 2003 and December 2008. All adult patients of either gender who presented with abdominal tuberculosis and were managed at our hospital during the study period were included in the study on the basis of convenience sampling. Numerical data were expressed as mean +/- standard deviation, while categorical data were analysed using SPSS version 10. Chi square test was conducted to compare categorical variables.

RESULTS

Of the 233 adult patients with abdominal tuberculosis who were part of the study, 110 (47.21%) were males and 123 (52.78%) females. The mean age was 28.21 +/- 5.75 years. Majority of our patients (80.68%) belonged to poor families. History of concomitant pulmonary tuberculosis was found in 23 (9.87%) patients. Family history of tuberculosis was found in 13 (5.57%) patients. Of the patients 157 (67.38%) presented with acute abdomen; strictures were the most common operative finding (n = 161; 69%); the patients needing hospitalisation were 204 (87.55%), with the mean hospital stay being 19.55 +/- 4.51 days. The in-hospital mortality was 5 (2.14%).

CONCLUSION

Abdominal tuberculosis was found prevalent in the population and predominantly affected the younger lot belonging to the poor socioeconomic strata. Majority of the cases were of primary intestinal variety, and in a small proportion it was secondary to pulmonary tuberculosis. Majority of the patients presented with complications such as acute intestinal obstruction, intestinal perforation and peritonitis, necessitating emergency laparotomy.

摘要

目的

记录三级医疗机构中腹部结核患者的流行病学概况及治疗结果。

方法

本描述性病例系列研究于2003年1月至2008年12月在伊斯兰堡巴基斯坦医学科学研究所(PIMS)外科进行。在研究期间,所有因腹部结核前来我院就诊并接受治疗的成年患者,基于方便抽样纳入本研究。数值数据以均值±标准差表示,分类数据采用SPSS 10版进行分析。采用卡方检验比较分类变量。

结果

本研究纳入的233例成年腹部结核患者中,男性110例(47.21%),女性123例(52.78%)。平均年龄为28.21±5.75岁。大多数患者(80.68%)来自贫困家庭。23例(9.87%)患者有合并肺结核病史。13例(5.57%)患者有结核家族史。157例(67.38%)患者表现为急腹症;狭窄是最常见的手术发现(n = 161;69%);需要住院治疗的患者有204例(87.55%),平均住院时间为19.55±4.51天。院内死亡率为5例(2.14%)。

结论

腹部结核在人群中普遍存在,主要影响社会经济地位低下的年轻人群。大多数病例为原发性肠道型,少数为继发于肺结核。大多数患者出现急性肠梗阻、肠穿孔和腹膜炎等并发症,需要急诊剖腹手术。

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