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[综合眼科门诊干眼知晓率的随机抽样调查]

[Randomly sampling survey of dry eye awareness in general eye clinic].

作者信息

Qiu Wei-qiang, Liu Zi-yuan, Ji Jing, Zeng Lin, Li Xue-min, Wang Wei

机构信息

Department of Ophthalmology, Peking University Third Hospital, Beijing, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2013 Mar;49(3):230-4.

Abstract

OBJECTIVE

To determine the dry eye awareness in the populations visiting general eye clinic.

METHODS

This was a cross-sectional study. A questionnaire about dry eye was designed and administrated to Peking University Third Hospital General Eye Clinic patients (n = 804) from June 2010 to June 2011. The questionnaire contents included general demographic characteristics, experience of health-related work, past medical history, medication history and ocular surface symptoms associated with dry eye, contact lens wearing, ocular operation history, etc. Chi-square and Binary logistic regression analysis was used to determine the influence of demographic and clinical features on awareness of dry eye.

RESULTS

Awareness of "dry eye" in the general eye clinical patients was relatively low (26.9%, 216/804). Participants whose age were between 40 and 60 years had better dry eye awareness (41.7%, 73/175) (χ(2) = 27.365, P = 0.000). Dry eye awareness of female was better than that of male [female: 33.8% (151/447), male: 18.2% (65/357), χ(2) = 24.500, P = 0.000]. Those who had been in health-related work (71.4%, 30/42), and whose friends or relatives were ophthalmologists (54.7%, 52/95) had better dry eye awareness (χ(2) = 31.582, 36.400; both P < 0.01). Participants with a history of rheumatoid arthritis (7/10) or diabetes mellitus (63.0%, 17/27) had better dry eye awareness (χ(2) = 32.301, 29.887;both P < 0.01). Those who had been using artificial tears (77.5%, 31/40), oral contraceptives (9/14), diuretics (10/18), sedatives (70.4%, 19/27) and anti-depression drugs (4/4) had better dry eye awareness (χ(2) = 54.928, 10.154, 7.713, 26.912, 10.943; all P < 0.01). Except frequently blinking (29.5%), participants who had ocular irrigating symptoms (all > 33.0%) had better awareness than those who had not (χ(2) = 7.831 - 32.522, all P < 0.01). Those who were allergic to environment irritating factors (all > 30.0%) had better awareness (χ(2) = 5.033 - 24.564, all P < 0.01). Participants who had medical history of ocular surgery (47.2%, 34/72), experience of wearing contact lens (33.2%, 94/283), who were diagnosed as dry eye (100.0%, 45/45) and who had regular ocular examinations (31.0%, 96/310) had better awareness (χ(2) = 4.321 - 129.763, all P < 0.01). Those who had visited general practitioners (14.8%, 16/108) had lower awareness than those who went to hospital of higher level (28.7%, 200/696) (χ(2) = 9.324, P = 0.002). The result of binary logistic regression analysis showed that gender, health-related working experience, relatives or friends working as Ophthalmologists, using artificial tears, oral contraceptives and sedatives, ocular irritations or environment sensitivity, eye surgeries and wearing contact lens were factors that affected dry eye awareness (OR > 1.000, P < 0.10).

CONCLUSIONS

Dry eye awareness in the population who visit general eye clinic is low. The knowledge of dry eye should be added to the patient education and public popularization.

摘要

目的

确定在综合眼科门诊就诊人群中对干眼的认知情况。

方法

这是一项横断面研究。设计了一份关于干眼的问卷,并于2010年6月至2011年6月对北京大学第三医院综合眼科门诊患者(n = 804)进行调查。问卷内容包括一般人口统计学特征、与健康相关工作经历、既往病史、用药史以及与干眼相关的眼表症状、佩戴隐形眼镜情况、眼部手术史等。采用卡方检验和二元逻辑回归分析来确定人口统计学和临床特征对干眼认知的影响。

结果

综合眼科门诊患者中对“干眼”的认知相对较低(26.9%,216/804)。年龄在40至60岁之间的参与者干眼认知较好(41.7%,73/175)(χ(2)=27.365,P = 0.000)。女性的干眼认知优于男性[女性:33.8%(151/447),男性:18.2%(65/357),χ(2)=24.500,P = 0.000]。从事与健康相关工作的人(71.4%,30/42)以及其朋友或亲属为眼科医生的人(54.7%,52/95)干眼认知较好(χ(2)=31.582,36.400;P均< 0.01)。有类风湿关节炎病史(7/10)或糖尿病病史(63.0%,17/27)的参与者干眼认知较好(χ(2)=32.301,29.887;P均< 0.01)。曾使用人工泪液(77.5%,31/40)、口服避孕药(9/14)、利尿剂(10/18)、镇静剂(70.4%,19/27)和抗抑郁药(4/4)的参与者干眼认知较好(χ(2)=54.928,10.154,7.713,26.912,10.943;P均< 0.01)。除频繁眨眼(29.5%)外,有眼部冲洗症状的参与者(均> 33.0%)比无此症状者认知更好(χ(2)=7.831 - 32.522,P均< 0.01)。对环境刺激因素过敏的参与者(均> 30.0%)认知更好(χ(2)=5.033 - 24.564,P均< 0.01)。有眼部手术病史(47.2%,34/72)、佩戴隐形眼镜经历(33.2%,94/283)、被诊断为干眼(100.0%,45/45)以及定期进行眼部检查的参与者(31.0%,96/310)认知更好(χ(2)=4.321 - 129.763,P均< 0.01)。看过全科医生的参与者(14.8%,16/108)比去上级医院就诊的参与者(28.7%,200/696)认知更低(χ(2)=9.324,P = 0.002)。二元逻辑回归分析结果显示,性别、与健康相关工作经历、亲属或朋友为眼科医生、使用人工泪液、口服避孕药和镇静剂、眼部刺激或环境敏感性、眼部手术和佩戴隐形眼镜是影响干眼认知的因素(OR > 1.000,P < 0.10)。

结论

在综合眼科门诊就诊人群中干眼认知较低。应将干眼知识纳入患者教育和公众普及内容中。

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