Li Bing-zhen, Hong Jing, Peng Rong-mei, Wang Xin, Ren Jing, Wu Ling-ling
Department of Ophthalmology, Peking University Third Hospital, Beijing, China.
Zhonghua Yan Ke Za Zhi. 2013 Mar;49(3):257-62.
To evaluate the influence of corneal thickness (CT) on the intraocular pressure (IOP) measurements, the agreement of IOP readings with I Care rebound tonometer (RBT) and Goldmann applanation tonometer (GAT), and the agreement of central and peripheral IOP values obtained by RBT.
Thirty-seven eyes of 34 patients after Descemet's stripping with automated endothelium keratoplasty (DSAEK) underwent CT measurement using anterior segment OCT (AS-OCT) followed by IOP evaluation with the GAT at corneal center and with the RBT at corneal center and at 1 mm from the limbus in the nasal and temporal directions. The mean IOP measurement by the RBT and measurement by the GAT were analysed by paired t test. Pearson correlation analysis were performed to assess the correlations between the measurement and the influence of CT on IOP values. Agreement between the tonometers was calculated using the Bland-Altman method.
IOP obtained by GAT was (16.2 ± 4.7) mm Hg (1 mm Hg = 0.133 kPa), and IOP obtained from central cornea, nasal cornea and temporal cornea by RBT were (16.0 ± 5.3) mm Hg, (17.4 ± 5.0) mm Hg and (17.1 ± 5.0) mm Hg, respectively. There was no statistical difference between the IOP on central cornea obtained by GAT and RBT (t = 0.77, P = 0.446), IOP on the peripheral cornea were higher than on central cornea by RBT (t = 3.24, 3.17, P = 0.003), and they were positively correlated (r = 0.869, 0.911, P < 0.05). The IOP readings showed positive relationship to CT values. Bland-Altman scatter plots showed reasonable inter-method agreement between each technique of IOP measurements.
After DSAEK, the IOP readings obtained by RBT or GAT show positive relationship to CT values. There are reasonable agreements between each technique of IOP measurements. Considering the special advantages, RBT is an effective method to observe the IOP changes after DSAEK.
评估角膜厚度（CT）对眼压（IOP）测量的影响、I Care 回弹眼压计（RBT）与 Goldmann 压平眼压计（GAT）测量眼压读数的一致性，以及 RBT 获得的中央和周边眼压值的一致性。
对 34 例接受 Descemet 膜剥离自动内皮角膜移植术（DSAEK）后的患者的 37 只眼，使用眼前节 OCT（AS - OCT）测量角膜厚度，随后在角膜中心用 GAT 测量眼压，并在角膜中心以及鼻侧和颞侧距角膜缘 1 mm 处用 RBT 测量眼压。通过配对 t 检验分析 RBT 和 GAT 测量的平均眼压。进行 Pearson 相关分析以评估测量值与 CT 对眼压值影响之间的相关性。使用 Bland - Altman 方法计算眼压计之间的一致性。
GAT 测得的眼压为（16.2±4.7）mmHg（1 mmHg = 0.133 kPa），RBT 在中央角膜、鼻侧角膜和颞侧角膜测得的眼压分别为（16.0±5.3）mmHg、（17.4±5.0）mmHg 和（17.1±5.0）mmHg。GAT 和 RBT 在中央角膜测得的眼压之间无统计学差异（t = 0.77，P = 0.446），RBT 测得的周边角膜眼压高于中央角膜眼压（t = 3.24，3.17，P = 0.003），且二者呈正相关（r = 0.869，0.911，P < 0.05）。眼压读数与 CT 值呈正相关。Bland - Altman 散点图显示各眼压测量技术之间具有合理的方法间一致性。
DSAEK 术后，RBT 或 GAT 测得的眼压读数与 CT 值呈正相关。各眼压测量技术之间具有合理的一致性。考虑到其特殊优势，RBT 是观察 DSAEK 术后眼压变化的有效方法。
