Sahin Afsun, Niyaz Leyla, Yildirim Nilgun
Eskisehir Osmangazi University Hospital, Department of Ophthalmology, Eskisehir, Meselik, Turkey.
Clin Exp Ophthalmol. 2007 May-Jun;35(4):335-9. doi: 10.1111/j.1442-9071.2007.01451.x.
To determine the agreement between the measurement of intraocular pressure (IOP) by the rebound tonometer (RBT) and by the Goldmann applanation tonometer (GAT) and to find out the effect of central corneal thickness (CCT) values on IOP measurements in glaucoma patients.
IOP was measured with the RBT and GAT, respectively, in 61 eyes of 61 glaucoma patients. CCT was measured using an ultrasonic pachymeter after all IOP determinations had been made. The mean IOP measurement by the RBT was compared with the measurement by the GAT, by Student's t-test. Bland-Altman analysis was performed to assess the clinical agreement between the two methods. The effect of CCT on measured IOP was explored by linear regression analysis.
The mean patient age was 56.7+/-21.1 years (range: 30-80 years). There were 32 (52.46%) women and 29 (47.54%) men in the study group. The mean IOP readings were 18.70+/-4.76 mmHg using the RBT, and 18.27+/-3.49 mmHg using the GAT. The difference was not statistically significant (mean difference 0.43+/-2.55, P=0.2). A frequency distribution of the differences demonstrated that in more than 80% of cases the IOP readings differed by <2.3 mmHg between the RBT and GAT. There was a strong correlation between the RBT and GAT readings (r=0.852, P<0.0001). The IOP measurements with the two methods were correlated with CCT (r=0.40, P=0.02 for the RBT and r=0.48, P<0.0001 for the GAT). The IOP increased 1.1 mmHg and 8 mmHg for every 100-microm increase in CCT for the GAT and RBT, respectively.
The RBT slightly overestimated the IOP value by 0.43 mmHg on average when compared with the GAT. Nevertheless, the RBT readings appeared to be more affected by the various thicknesses of different corneas when compared with those obtained using the GAT.
确定回弹式眼压计（RBT）与Goldmann压平眼压计（GAT）测量眼压（IOP）之间的一致性，并探究中央角膜厚度（CCT）值对青光眼患者眼压测量的影响。
分别用RBT和GAT测量61例青光眼患者的61只眼的眼压。在所有眼压测定完成后，使用超声角膜测厚仪测量CCT。通过Student t检验比较RBT和GAT测量的平均眼压。进行Bland-Altman分析以评估两种方法之间的临床一致性。通过线性回归分析探究CCT对测量眼压的影响。
患者平均年龄为56.7±21.1岁（范围：30 - 80岁）。研究组中有32名女性（52.46%）和29名男性（47.54%）。使用RBT测量的平均眼压读数为18.70±4.76 mmHg，使用GAT测量的为18.27±3.49 mmHg。差异无统计学意义（平均差异0.43±2.55，P = 0.2）。差异的频率分布表明，在超过80%的病例中，RBT和GAT测量的眼压读数相差<2.3 mmHg。RBT和GAT读数之间存在强相关性（r = 0.852，P < 0.0001）。两种方法测量的眼压与CCT相关（RBT的r = 0.40，P = 0.02；GAT的r = 0.48，P < 0.0001）。对于GAT和RBT，CCT每增加100微米，眼压分别升高1.1 mmHg和8 mmHg。
与GAT相比，RBT平均略微高估眼压值0.43 mmHg。然而，与使用GAT获得的读数相比，RBT读数似乎受不同角膜厚度的影响更大。
