Tafazoli Ali, Tafazoli Moghadam Ehsan
Dept. Clinical Pharmacy, Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Dept. of Orthodontics, School of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran.
J Dent (Shiraz). 2020 Dec;21(4):249-262. doi: 10.30476/DENTJODS.2020.83204.1045.
Herbal products are increasingly growing in the oral care market. Some of the related herbal compounds in this field have considerable clinical evidence for use in mouthwashes in their background. Camellia sinensis or tea plant has attracted numerous researchers of dentistry and pharmaceutical sciences, in recent years, for its biologic and medicinal properties. The effects such as anti-septic, anti-oxidative, and anti-inflammatory activities have made this plant a suitable candidate for preparation of mouthwashes. In this systematic review, we tried to find, evaluate, and categorize the sparse evidence in medical literature about Camellia sinensis mouthwashes. We explored three scientific databases with keywords including tea, dental care, Camellia sinensis, and mouthwashes and found 69 relevant studies including 41 randomized controlled trials (RCTs), which are generally proposing anti-microbial, anti-plaque, and analgesic indications for these tea formulations. Considering the main trend in clinical evidence and favorable safety profile, Camellia sinensis products are able to act as antiseptic, anti-plaque, and anti-inflammatory agents and can be used as useful mouthwashes in the future clinical studies and practice.
草药产品在口腔护理市场中的份额日益增长。该领域一些相关的草药化合物在用于漱口水方面有大量临床证据支持。近年来，茶树因其生物学和药用特性吸引了众多牙科和制药科学领域的研究人员。其具有的抗菌、抗氧化和抗炎等作用使这种植物成为制备漱口水的合适选择。在本系统评价中，我们试图查找、评估并归类医学文献中关于茶树漱口水的稀少证据。我们用包括茶、牙齿护理、茶树和漱口水等关键词检索了三个科学数据库，共找到69项相关研究，其中包括41项随机对照试验（RCT），这些研究总体上提出了这些茶制剂具有抗菌、防菌斑和止痛的适应证。考虑到临床证据的主要趋势和良好的安全性，茶树产品能够作为抗菌、防菌斑和抗炎剂，可在未来的临床研究和实践中用作有效的漱口水。
