Erbasar Guzin Neda Hasanoglu, Kaplan Volkan, Cigerim Levent, Konarili Fatma Nur, Sahin Mukerrem
Ankara Yıldırım Beyazıt University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Ankara, Turkey.
Tekirdag Namik Kemal University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Tekirdag, Turkey.
Clin Oral Investig. 2023 Jul;27(7):3817-3826. doi: 10.1007/s00784-023-04999-z. Epub 2023 Apr 3.
This study aimed to evaluate the effects of different concentrations of boric acid (BA) combined with chlorhexidine (CHX) mouthwash on postoperative complications and periodontal healing following impacted third molar surgery.
A total of 80 patients were randomly divided into eight groups. The patients in the study groups received different concentrations of BA ranging from 0.1% to 2.5% combined with CHX or 2% BA mouthwash alone. The control group received CHX mouthwash alone. The scores of self-reported pain and jaw dysfunction, trismus, edema, number of analgesics used, and periodontal parameters were compared between the groups.
2.5% BA + CHX group had significantly lower pain and facial swelling values during the follow-up period. 2% BA + CHX group reported significantly lower jaw dysfunction scores on the fourth and fifth postoperative days. The control group showed significantly higher values for pain, jaw dysfunction, and facial swelling than other groups. No significant differences were found between the groups regarding trismus, analgesic use, and periodontal variables.
The combination of higher concentrations of BA with CHX was more effective in reducing pain, jaw dysfunction, and swelling following impacted third molar surgery than CHX mouthwash alone.
The combination of BA and CHX showed better results than the gold standard CHX mouthwash in reducing postoperative complications related to surgical removal of impacted third molars without any adverse effects. This new combination can be an effective alternative to traditional mouthwashes after impacted third molar surgery to ensure oral hygiene.
本研究旨在评估不同浓度硼酸（BA）与氯己定（CHX）漱口水联合使用对阻生第三磨牙拔除术后并发症及牙周愈合的影响。
总共80例患者被随机分为八组。研究组患者接受浓度范围为0.1%至2.5%的不同浓度BA与CHX联合使用，或单独使用2% BA漱口水。对照组仅接受CHX漱口水。比较各组间自我报告的疼痛和下颌功能障碍、牙关紧闭、水肿、使用的止痛药物数量以及牙周参数的评分。
在随访期间，2.5% BA + CHX组的疼痛和面部肿胀值显著更低。2% BA + CHX组在术后第四天和第五天报告的下颌功能障碍评分显著更低。对照组的疼痛、下颌功能障碍和面部肿胀值显著高于其他组。在牙关紧闭、止痛药物使用和牙周变量方面，各组间未发现显著差异。
高浓度BA与CHX联合使用在减轻阻生第三磨牙拔除术后的疼痛、下颌功能障碍和肿胀方面比单独使用CHX漱口水更有效。
在减少与阻生第三磨牙拔除手术相关的术后并发症方面，BA和CHX联合使用比金标准CHX漱口水效果更好，且无任何不良反应。这种新的联合用药可作为阻生第三磨牙拔除术后传统漱口水的有效替代方案，以确保口腔卫生。
