Department of Pharmacy, University of Naples Federico II, Via D. Montesano 49, 80131 Napoli, Italy.
Food Chem. 2013 Dec 1;141(3):2379-84. doi: 10.1016/j.foodchem.2013.04.128. Epub 2013 May 24.
The leaves at different processing stages of a single tea cultivar in order to obtain white (WT), green (GT) and black tea (BT) samples, were analysed. The capacities of tea polyphenolics to influence the glucose and lipid metabolism in HepG2 cell lines were evaluated. WT appeared the most active in reducing the glucose and cholesterol uptake (+17.7% and +32.4% in the glucose and cholesterol cell medium concentration, respectively). Incubation with WT enhanced LDL receptor binding activity by 40% (+20% for GT and +0% for BT) and led to an increase in HDL cell medium concentration of 33.3% (+20% for GT and +0% for BT). Finally, WT revealed the best inhibition capacity against lipase activity, and triglyceride levels in the cell medium increased by 400% (+382.6% for GT and +191.3% for BT). The present study intended to contribute to the little knowledge about the potential health benefits of white tea in individuals affected by metabolic syndrome.
为了获得白茶（WT）、绿茶（GT）和红茶（BT）样品，对单一茶树品种的不同加工阶段的叶片进行了分析。评估了茶多酚对 HepG2 细胞系中葡萄糖和脂质代谢的影响。WT 在降低葡萄糖和胆固醇摄取方面最为活跃（葡萄糖和胆固醇细胞培养基浓度分别增加+17.7%和+32.4%）。用 WT 孵育可使 LDL 受体结合活性增加 40%（GT 为+20%，BT 为+0%），并使 HDL 细胞培养基浓度增加 33.3%（GT 为+20%，BT 为+0%）。最后，WT 显示出对脂肪酶活性的最佳抑制能力，细胞培养基中的甘油三酯水平增加了 400%（GT 为+382.6%，BT 为+191.3%）。本研究旨在为代谢综合征患者白茶的潜在健康益处提供一些知识。
