Anaeigoudari Akbar, Safari Hamidreza, Khazdair Mohammad Reza
Department of Physiology, School of Medicine, Jiroft University of Medical Science, Jiroft, Iran.
Torbat Jam Faculty of Medical Sciences, Torbat Jam, Iran.
Front Pharmacol. 2021 Nov 17;12:762182. doi: 10.3389/fphar.2021.762182. eCollection 2021.
Metabolic disorders (MD) can disturb intracellular metabolic processes. A metabolic disorder can be resulted from enzyme deficits or disturbances in function of various organs including the liver, kidneys, pancreas, cardiovascular system, and endocrine system. Some herbs were used traditionally for spices, food additives, dietary, and medicinal purposes. Medicinal plants possess biological active compounds that enhance human health. We aimed to provide evidence about therapeutic effects of some medicinal herbs on MD. PubMed, Scopus, and Google Scholar were explored for publications linked to MD until February 2021. The most literature reports that were published in the last 10 years were used. All types of studies such as animal studies, clinical trials, and studies were included. The keywords included "Metabolic disorders," " L.," "Thymoquinone," "White tea"OR " L." "catechin," and " L." OR "garlic" were searched. Based on the results of scientific studies, the considered medicinal plants and their active components in this review have been able to exert the beneficial therapeutic effects on obesity, diabetes mellitus and non-alcoholic fatty liver disease. These effects are obvious by inhibition of lipid peroxidation, suppression of inflammatory reactions, adjustment of lipid profile, reduction of adipogenesis and regulation of blood glucose level.
代谢紊乱(MD)会干扰细胞内的代谢过程。代谢紊乱可能由酶缺乏或包括肝脏、肾脏、胰腺、心血管系统和内分泌系统在内的各种器官功能紊乱引起。一些草药传统上被用作香料、食品添加剂、膳食和药用。药用植物含有增强人类健康的生物活性化合物。我们旨在提供一些药草对MD治疗效果的证据。截至2021年2月,我们在PubMed、Scopus和谷歌学术上搜索了与MD相关的出版物。使用了过去10年发表的最多的文献报告。纳入了所有类型的研究,如动物研究、临床试验和其他研究。搜索的关键词包括“代谢紊乱”、“L.”、“百里醌”、“白茶”或“L.”、“儿茶素”以及“L.”或“大蒜”。基于科学研究的结果,本综述中考虑的药用植物及其活性成分能够对肥胖、糖尿病和非酒精性脂肪肝病发挥有益的治疗作用。这些作用通过抑制脂质过氧化、抑制炎症反应、调节血脂、减少脂肪生成和调节血糖水平而明显体现。