Department of Biochemistry, School of Biochemistry, Genetics and Microbiology, University of KwaZulu-Natal (Westville Campus), Durban 4000, South Africa.
Phytomedicine. 2011 Dec 15;19(1):25-31. doi: 10.1016/j.phymed.2011.06.025. Epub 2011 Jul 30.
White tea (WT) is very similar to green tea (GT) but it is exceptionally prepared only from the buds and young tea leaves of Camelia sinensis plant while GT is prepared from the matured tea leaves. The present study was investigated to examine the effects of a 0.5% aqueous extract of WT in a streptozotocin-induced diabetes model of rats. Six-week-old male Sprague-Dawley rats were divided into 3 groups of 6 animals in each group namely: normal control (NC), diabetic control (DBC) and diabetic white tea (DWT). Diabetes was induced by an intraperitoneal injection of streptozotocin (65 mg/kg BW) in DBC and DWT groups except the NC group. After 4 weeks feeding of 0.5% aqueous extracts of WT, the drink intake was significantly (P<0.05) increased in the DWT group compared to the DBC and NC groups. Blood glucose concentrations were significantly decreased and glucose tolerance ability was significantly improved in the DWT group compared to the DBC group. Liver weight and liver glycogen were significantly increased and serum total cholesterol and LDL-cholesterol were significantly decreased in the DWT group compared to the DBC group. The food intake, body weight gain, serum insulin and fructosamine concentrations were not influenced by the consumption of WT. Data of this study suggest that the 0.5% aqueous extract of WT is effective to reduce most of the diabetes associated abnormalities in a steptozotocin-induced diabetes model of rats.
白茶（WT）与绿茶（GT）非常相似，但它是由茶树的芽和嫩叶特别制成的，而 GT 是由成熟的茶叶制成的。本研究旨在研究 0.5%白茶水提物对链脲佐菌素诱导的糖尿病大鼠模型的影响。将 6 周龄雄性 Sprague-Dawley 大鼠分为 3 组，每组 6 只，分别为：正常对照组（NC）、糖尿病对照组（DBC）和糖尿病白茶组（DWT）。除 NC 组外，DBC 和 DWT 组大鼠通过腹腔注射链脲佐菌素（65mg/kgBW）诱导糖尿病。在给予 0.5%WT 水提取物 4 周后，与 DBC 和 NC 组相比，DWT 组大鼠的饮水量显著增加（P<0.05）。与 DBC 组相比，DWT 组大鼠的血糖浓度显著降低，葡萄糖耐量能力显著提高。与 DBC 组相比，DWT 组大鼠的肝重和肝糖原显著增加，血清总胆固醇和 LDL 胆固醇显著降低。WT 的摄入对大鼠的食物摄入量、体重增加、血清胰岛素和果糖胺浓度没有影响。本研究的数据表明，0.5%WT 水提物可有效减轻链脲佐菌素诱导的糖尿病大鼠模型中的大多数与糖尿病相关的异常。
