Saha K, Rao K N, Chattopadhya D, Lakshmi V, Gadi S, Dutta Banik N D
Department of Immunology, Vallabhbhai Patel Chest Institute, University of Delhi, India.
Eur J Clin Nutr. 1990 Jun;44(6):471-9.
This paper describes a cross-sectional study of the physical development of a high-risk group of 182 socially deprived healthy children of leprosy patients ranging from preschool age to early teens. They were rescued at the age of 4 years from the distress of leprosy colonies where they were born, and brought up in Government Homes (Preventorium) under better environmental conditions. Of them 135 children could be followed clinically for 10 years for the development of childhood leprosy. Another 94 children of leprosy patients living with their parents were included for comparison. A group of 158 normal children of similar economic status and age group were included as controls. It was observed that, although better environment, food and training were provided in the Preventorium, so that the children could be brought into the national mainstream, nevertheless 5 children developed an indeterminate type of leprosy during the course of 10 years. This is the first report of growth and development of children of leprosy patients from the Indian sub-continent.
本文描述了一项横断面研究，该研究针对182名社会经济条件差的麻风病患者健康子女这一高危群体，他们的年龄从学龄前到青少年早期。这些孩子在4岁时从出生所在的麻风病隔离区的困境中被解救出来，并在政府福利院（防治所）中在更好的环境条件下抚养长大。其中135名儿童接受了为期10年的临床随访，以观察儿童麻风病的发展情况。另外94名与父母生活在一起的麻风病患者子女被纳入作为对照。一组158名经济状况和年龄组相似的正常儿童被纳入作为对照组。研究发现，尽管防治所提供了更好的环境、食物和培训，以使这些孩子能够融入国家主流群体，但仍有5名儿童在10年期间患上了未定类麻风病。这是来自印度次大陆麻风病患者子女生长发育情况的首份报告。
