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人胃液壁细胞成分的酸浓度与最大酸分泌量的关系。

Relation of the acid concentration of the parietal component of the gastric juice to the maximal acid output in man.

作者信息

Ligny G, Smets P

出版信息

Biomedicine. 1977 Dec;26(6):396-9.

PMID:23874
Abstract

In two populations of patients tested with S.C. histamine and with I.V. pentagastrin the values of the theoretical acid [H+]O and chloride [Cl-]O concentration of the parietal secretion for a zero value of sodium from the relationships H+ = f ([Na+]) and Cl- = f ([Na+]) were calculated. In both populations a decrease of [H+]O and [Cl-]o for low acid outputs was observed. The parallel decrease of the calculated H+ and Cl- ion concentration of the parietal component for low acid outputs gives indirect evidence that parietal secretion could become hypotonic in patients whose acid output is low.

摘要

在两组分别用皮下注射组胺和静脉注射五肽胃泌素进行检测的患者群体中,根据H⁺ = f([Na⁺])和Cl⁻ = f([Na⁺])的关系,计算了钠值为零时壁细胞分泌液中理论酸[H⁺]O和氯[Cl⁻]O的浓度。在这两组群体中,均观察到低酸分泌量时[H⁺]O和[Cl⁻]O降低。低酸分泌量时壁细胞成分中计算出的H⁺和Cl⁻离子浓度平行降低,间接证明了酸分泌量低的患者壁细胞分泌液可能变为低渗。

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