Happé R P, De Bruijne J J
Res Vet Sci. 1982 Sep;33(2):232-9.
An orogastric aspiration technique is presented for the estimation of pentagastrin stimulated gastric secretion in the anaesthetised dog. Reference values for volume, pH and hydrogen ion output, 'acidity' and hydrochloric acid output, chloride, sodium, potassium and pepsin outputs were measured and calculated in 23 clinically healthy dogs. It was concluded that 30 and 45 minute hydrogen ion, hydrochloric acid and chloride peak outputs were the most suitable parameters for the acid secreting capacity of the parietal cells. Reference values for 30 and 45 minute peak outputs were respectively 1.63 to 3.61 and 1.50 to 3.35 mmol per hour per kg0.75 (hydrogen ion), 1.86 to 3.64 and 1.65 to 3.42 mmol per hour per kg0.75 (hydrochloric acid) and 2.35 to 4.13 and 1.98 to 3.91 mmol per hour per kg0.75 (chloride). Reproducibility of pepsin outputs was so poor that they cannot be used as parameters for gastric secretory capacity.
本文介绍了一种用于评估麻醉犬中五肽胃泌素刺激的胃液分泌的经口胃抽吸技术。在23只临床健康的犬中测量并计算了胃液体积、pH值、氢离子输出量、“酸度”、盐酸输出量、氯离子、钠离子、钾离子和胃蛋白酶输出量的参考值。得出的结论是，30分钟和45分钟时的氢离子、盐酸和氯离子峰值输出量是评估壁细胞胃酸分泌能力的最合适参数。30分钟和45分钟峰值输出量的参考值分别为每小时每千克0.75体表面积1.63至3.61毫摩尔和1.50至3.35毫摩尔（氢离子）、每小时每千克0.75体表面积1.86至3.64毫摩尔和1.65至3.42毫摩尔（盐酸）以及每小时每千克0.75体表面积2.35至4.13毫摩尔和1.98至3.91毫摩尔（氯离子）。胃蛋白酶输出量的重复性很差，因此不能用作胃液分泌能力的参数。
