Department of Health Economics and Health Services Research, Hamburg Center for Health Economics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
PLoS One. 2013 Jul 18;8(7):e70018. doi: 10.1371/journal.pone.0070018. Print 2013.
To analyse predictors of costs in dementia from a societal perspective in a longitudinal setting.
Healthcare resource use and costs were assessed retrospectively using a questionnaire in four waves at 6-month intervals in a sample of dementia patients (N = 175). Sociodemographic data, dementia severity and comorbidity at baseline, cognitive impairment and impairment in basic and instrumental activities of daily living were also recorded. Linear mixed regression models with random intercepts for individuals were used to analyse predictors of total and sector-specific costs.
Impairment in activities of daily living significantly predicted total costs in dementia patients, with associations between basic activities of daily living and formal care costs on the one and instrumental activities of daily living and informal care costs on the other hand. Nursing home residence was associated with lower total costs than residence in the community. There was no effect of cognition on total or sector-specific costs.
Cognitive deficits in dementia are associated with costs only via their effect on the patients' capacity for activities of daily living. Transition into a nursing home may reduce total costs from a societal perspective, owing to the fact that a high amount of informal care required by severely demented patients prior to transition into a nursing home may cause higher costs than inpatient nursing care.
从社会角度分析纵向设置中痴呆症的成本预测因素。
在痴呆症患者样本中(N=175),使用问卷在 6 个月的间隔内进行了 4 个时间点的回顾性评估,以评估医疗保健资源的使用和成本。基线时还记录了人口统计学数据、痴呆严重程度和合并症、认知障碍以及基本和工具性日常生活活动能力的损害。使用具有个体随机截距的线性混合回归模型来分析总费用和特定部门费用的预测因素。
日常生活活动能力的损害显著预测了痴呆症患者的总费用,其中基本日常生活活动与正规护理费用之间存在关联,而工具性日常生活活动与非正式护理费用之间存在关联。与居住在社区相比,居住在养老院的患者总费用较低。认知能力对总费用或特定部门费用没有影响。
痴呆症的认知缺陷仅通过对患者日常生活活动能力的影响与费用相关。从社会角度来看,进入养老院可能会降低总费用,因为在进入养老院之前,严重痴呆症患者需要大量的非正式护理,这可能导致费用高于住院护理。