新辅助化疗后行保留生育功能手术治疗ⅠB1 期宫颈癌的研究
Neoadjuvant chemotherapy followed by fertility-sparing surgery for women with stage IB1 cervical cancer.
机构信息
Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Beijing, China.
出版信息
J Gynecol Oncol. 2013 Jul;24(3):287-90. doi: 10.3802/jgo.2013.24.3.287. Epub 2013 Jul 4.
Abstract
Fertility-sparing surgery was optimal to patients with tumor diameter smaller than 2 cm. For patients with larger tumors, neoadjuvant chemotherapy can debulk the tumor and offer the chance of surgery. We report 2 cases of stage IB1 cervical cancer treated by neoadjuvant chemotherapy and fertility-sparing surgery. Relevant literature was reviewed. Its safety, efficacy, and reproductive outcome need to be validated in the future.
摘要
对于肿瘤直径小于 2 cm 的患者，保留生育功能的手术是最佳选择。对于肿瘤较大的患者，新辅助化疗可以使肿瘤缩小，并提供手术机会。我们报告了 2 例接受新辅助化疗和保留生育功能手术治疗的 IB1 期宫颈癌患者。回顾了相关文献。其安全性、疗效和生殖结局有待进一步验证。
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