Department of Radiology, Mayo Clinic, Rochester MN, USA.
Magn Reson Imaging. 2013 Oct;31(8):1263-70. doi: 10.1016/j.mri.2013.06.008. Epub 2013 Jul 20.
A novel 3D breath-held Dixon fat-water separated balanced steady state free precession (b-SSFP) sequence for MR cholangiopancreatography (MRCP) is described and its potential clinical utility assessed in a series of patients. The main motivation is to develop a robust breath-held alternative to the respiratory gated 3D Fast Spin Echo (FSE) sequence, the current clinical sequence of choice for MRCP. Respiratory gated acquisitions are susceptible to motion artifacts and blurring in patients with significant diaphragmatic drift, erratic respiratory rhythms or sleep apnea. A two point Dixon fat-water separation scheme was developed which eliminates signal loss arising from B0 inhomogeneity effects and minimizes artifacts from perturbation of the b-SSFP steady state. Preliminary results from qualitative analysis of 49 patients demonstrate robust performance of the 3D Dixon b-SSFP sequence with diagnostic image quality acquired in a 20-24s breath-hold.
一种新型的 3D 屏气 Dixon 水脂分离平衡稳态自由进动（b-SSFP）序列，用于磁共振胆胰管成像（MRCP），在一系列患者中评估其潜在的临床应用价值。主要动机是开发一种稳健的屏气替代呼吸门控 3D 快速自旋回波（FSE）序列，这是目前用于 MRCP 的首选临床序列。呼吸门控采集容易受到运动伪影和模糊的影响，在有明显膈肌漂移、不规则呼吸节律或睡眠呼吸暂停的患者中。开发了一种两点 Dixon 水脂分离方案，该方案消除了由于 B0 不均匀性效应引起的信号损失，并最大限度地减少了由于 b-SSFP 稳态的扰动引起的伪影。对 49 名患者的定性分析初步结果表明，3D Dixon b-SSFP 序列具有稳健的性能，在 20-24 秒的屏气时间内可获得诊断质量的图像。
