Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Iwate, Japan.
Infect Immun. 2013 Oct;81(10):3627-31. doi: 10.1128/IAI.00550-13. Epub 2013 Jul 22.
Staphylococcal enterotoxins (SEs) are a common causative agent of food poisoning. Recently, many new SE-like (SEl) toxins have been reported, although the role of SEls in food poisoning remains unclear. In this study, the emetic potentials of SElK, SElL, SElM, SElN, SElO, SElP, and SElQ were assessed using a monkey-feeding assay. All the SEls that were tested induced emetic reactions in monkeys at a dose of 100 μg/kg, although the numbers of affected monkeys were significantly smaller than the numbers that were affected after consuming SEA or SEB. This result suggests that these new SEs may play some role in staphylococcal food poisoning.
葡萄球菌肠毒素（SEs）是一种常见的食物中毒致病因子。最近，已经报道了许多新的类葡萄球菌肠毒素（SEls），尽管 SEls 在食物中毒中的作用仍不清楚。在这项研究中，通过猴子喂养试验评估了 SElK、SElL、SElM、SElN、SElO、SElP 和 SElQ 的呕吐潜力。所有测试的 SEls 在 100μg/kg 的剂量下都能引起猴子的呕吐反应，尽管受影响的猴子数量明显少于摄入 SEA 或 SEB 后的数量。这一结果表明，这些新的 SEs 可能在葡萄球菌食物中毒中发挥一定作用。
