SPECT/CT 在乳腺癌患者前哨淋巴结检测中的作用。
Role of SPECT/CT in sentinel lymph node detection in patients with breast cancer.
机构信息
From the *Nuclear Medicine Department, Saint Louis Hospital, APHP, Paris, and †UCK, U728 INSERM, IUH, Paris, France; ‡Department of Radiology, University of Southern California, Los Angeles, CA; and §Department of Nuclear Medicine, Santa Maria della Misericordia Hospital, Rovigo, Italy.
出版信息
Clin Nucl Med. 2014 May;39(5):431-6. doi: 10.1097/RLU.0b013e31829af8c0.
AIM
The purpose of this study was to conduct a systematic review of the published literature to assess the role (indications, advantages, and limitations) of SPECT/CT for the detection of sentinel lymph node (SLN) in breast cancer.
METHODS
The authors searched PubMed for published literature in English addressing this topic.
RESULTS
Eleven studies, published since 2006, focused on the role and value of SPECT/CT for SLN detection (SLND). They showed that SPECT/CT improved sentinel node detection and anatomical localization. One study suggested that SPECT/CT may provide a more accurate staging. Limitations for SLND with SPECT/CT include extra time and inconvenience for the patient and additional radiation dose.
CONCLUSIONS
SPECT/CT is a valuable tool for SLND, especially in difficult cases, when planar lymphoscintigraphy shows no SLN or unexpected lymphatic drainage.
目的
本研究旨在对已发表的文献进行系统综述，评估单光子发射型计算机断层扫描/计算机断层扫描（SPECT/CT）在乳腺癌前哨淋巴结（SLN）检测中的作用（适应证、优势和局限性）。
方法
作者检索了 PubMed 上发表的关于该主题的英文文献。
结果
自 2006 年以来，11 项研究集中探讨了 SPECT/CT 在 SLN 检测（SLND）中的作用和价值。结果表明，SPECT/CT 提高了前哨淋巴结的检测和解剖定位能力。有一项研究表明，SPECT/CT 可能提供更准确的分期。SPECT/CT 进行 SLND 的局限性包括患者需要额外的时间和不便，以及额外的辐射剂量。
结论
SPECT/CT 是 SLND 的一种有价值的工具，特别是在平面淋巴闪烁显像显示无 SLN 或意外淋巴引流的困难情况下。
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