University of Medicine and Pharmacy & Cardiovascular Disease and Transplant Institute, Gh. Marinescu street 36, 540139 Târgu Mureş, Romania.
Europace. 2013 Aug;15(8):1223-5. doi: 10.1093/europace/eut227.
Although it is well known that silent atrial fibrillation (AF) is associated with morbidity and mortality rates similar to those of symptomatic AF, no specific strategy for screening and management of this form of AF has been advocated. The purpose of this survey was to identify current practices for the diagnosis and management of silent AF. This survey is based on an electronic questionnaire sent to the European Heart Rhythm Association Research Network partners. Responses were received from 33 centres in 16 countries. The preferred screening methods for silent AF in patients with rhythm control by pharmacological therapy was 12-lead electrocardiogram (ECG) at outpatient visits (31.3%) and periodical 24 h Holter ECG recordings (34.4%), while after pulmonary vein isolation the corresponding figures were 6.3 and 65.6%, respectively. No consensus has been reached concerning the therapeutic approach for such patients. Most responders preferred rate control over rhythm control in patients with silent AF, although some favoured pulmonary vein isolation in young patients. However, oral anticoagulant therapy in patients at high thromboembolic risk was considered mandatory by most, provided that at least one episode of silent AF was documented, without recommending further investigations. The results of this survey have confirmed that there is currently no consensus regarding the screening and management of patients with silent AF and that clinical practice is not always consistent with the few existing evidence-based recommendations.
虽然众所周知,无症状心房颤动(AF)与有症状 AF 的发病率和死亡率相似,但尚未提倡针对这种形式的 AF 的特定筛查和管理策略。本调查的目的是确定无症状 AF 的诊断和管理现状。该调查基于向欧洲心律协会研究网络合作伙伴发送的电子问卷。来自 16 个国家的 33 个中心做出了回应。在通过药物治疗进行节律控制的患者中,无症状 AF 的首选筛查方法是门诊时的 12 导联心电图(ECG)(31.3%)和定期 24 小时 Holter ECG 记录(34.4%),而在肺静脉隔离后,相应的数字分别为 6.3%和 65.6%。对于这些患者,尚未就治疗方法达成共识。大多数应答者倾向于对无症状 AF 患者进行心率控制而非节律控制,尽管一些人赞成对年轻患者进行肺静脉隔离。然而,大多数人认为,只要有至少一次无症状 AF 的记录,就必须对血栓栓塞风险高的患者进行口服抗凝治疗,而无需进一步检查,同时建议进行口服抗凝治疗。这项调查的结果证实,目前对于无症状 AF 患者的筛查和管理尚未达成共识,临床实践并不总是符合少数现有的基于证据的建议。