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影响儿童单侧尿路结石体外冲击波碎石术治疗效果的因素:一项17年单中心经验

Factors affecting the outcome of extracorporeal shock wave lithotripsy for unilateral urinary stones in children: a 17-year single-institute experience.

作者信息

Jeong U-Seok, Lee Sinwoo, Kang Junghun, Han Deok Hyun, Park Kwan Hyun, Baek Minki

机构信息

Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

Korean J Urol. 2013 Jul;54(7):460-6. doi: 10.4111/kju.2013.54.7.460. Epub 2013 Jul 15.

Abstract

PURPOSE

Extracorporeal shock wave lithotripsy (ESWL) is a first-line treatment for pediatric urinary stone disease. We aimed to determine the factors affecting the outcome of ESWL for unilateral urinary stones in children.

MATERIALS AND METHODS

A total of 81 pediatric patients aged 0 to 16 years with urinary stones treated by ESWL from January 1995 through May 2012 were retrospectively reviewed. All patients were required to have unilateral urinary stone disease. Children who underwent other surgical procedures before ESWL were excluded. Outcomes evaluated after ESWL were the stone-free rate at 3 months after ESWL, success within a single session, and success within three sessions. Factors affecting the success within three sessions were also analyzed.

RESULTS

The final analysis was for 42 boys and 22 girls (mean age, 9.2±5.2 years). Of these 64 patients, 58 (90.6%) were treated by ESWL without other surgical procedures and 54 (84.4%) were successfully treated within three ESWL sessions. In the multivariate analysis, multiplicity (odds ratio [OR], 0.080; 95% confidence interval [CI], 0.012 to 0.534; p=0.009) and large stone size (>10 mm; OR, 0.112; 95% CI, 0.018 to 0.707; p=0.020) were significant factors that decreased the success rate within three ESWL sessions.

CONCLUSIONS

Most of the pediatric urinary stone patients in our study (90.6%) were successfully treated by ESWL alone without additional procedures. If a child has a large urinary stone (>10 mm) or multiplicity, clinicians should consider that several ESWL sessions might be needed for successful stone fragmentation.

摘要

目的

体外冲击波碎石术(ESWL)是小儿泌尿系统结石疾病的一线治疗方法。我们旨在确定影响小儿单侧泌尿系统结石ESWL治疗效果的因素。

材料与方法

回顾性分析了1995年1月至2012年5月期间接受ESWL治疗的81例0至16岁泌尿系统结石患儿。所有患者均为单侧泌尿系统结石疾病。排除在ESWL治疗前接受过其他外科手术的患儿。ESWL治疗后评估的结果包括ESWL治疗后3个月的结石清除率、单次治疗成功以及三次治疗内成功。还分析了影响三次治疗内成功的因素。

结果

最终分析纳入42例男孩和22例女孩(平均年龄9.2±5.2岁)。在这64例患者中,58例(90.6%)仅接受ESWL治疗而未进行其他外科手术,54例(84.4%)在三次ESWL治疗内成功治愈。多因素分析显示,结石多发(比值比[OR],0.080;95%置信区间[CI],0.012至0.534;p = 0.009)和结石直径较大(>10 mm;OR,0.112;95%CI,0.018至0.707;p = 0.020)是降低三次ESWL治疗内成功率的显著因素。

结论

我们研究中的大多数小儿泌尿系统结石患者(90.6%)仅通过ESWL即可成功治疗,无需额外手术。如果儿童患有较大的泌尿系统结石(>10 mm)或结石多发,临床医生应考虑可能需要多次ESWL治疗才能成功碎石。

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