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香港成年人的多溴二苯醚(PBDEs)膳食暴露:首次香港总膳食研究结果。

Dietary exposure of the Hong Kong adult population to polybrominated diphenyl ethers (PBDEs): results of the first Hong Kong Total Diet Study.

机构信息

a Food and Environmental Hygiene Department , Centre for Food Safety, Hong Kong Special Administrative Region , Hong Kong , China.

出版信息

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013;30(10):1780-7. doi: 10.1080/19440049.2013.820355. Epub 2013 Jul 26.

Abstract

Polybrominated diphenyl ethers (PBDEs) are a group of industrial chemicals that are persistent and can bioaccumulate. In the first Hong Kong Total Diet Study, the dietary exposure of Hong Kong adults to PBDEs was estimated to assess the associated health risks. Food samples, which represented the Hong Kong people's diet, were collected and prepared in table-ready form for analysis. Concentrations of PBDEs were determined in 142 composite samples. The dietary exposures were estimated by combining the analytical results with the local food consumption data of the adults. The mean and 95th percentile of dietary PBDEs exposures of the Hong Kong people were 1.34 and 2.90 ng kg(-1) body weight day(-1), respectively. The main dietary source of PBDEs was "fish and seafood and their products", which contributed 27.3% of the total exposure, followed by "meat, poultry and game and their products" (20.7%), "cereals and their products" (15.9%), and "fats and oils" (15.9%). The large margins of exposure (MOE) (>2.5) calculated following the European Food Safety Authority (EFSA) approach for four important congeners, BDE-47, BDE-99, BDE-153 and BDE-209, indicate that the estimated dietary exposures are unlikely to be a significant health concern.

摘要

多溴二苯醚(PBDEs)是一组持久性的工业化学物质,能够生物累积。在首次香港总膳食研究中,通过评估香港成年人的多溴二苯醚膳食暴露量来估计相关健康风险。采集了具有代表性的食物样本,这些样本代表了香港人的饮食,并以即食形式准备好进行分析。在 142 个复合样本中测定了多溴二苯醚的浓度。通过将分析结果与成年人的本地食物消费数据相结合,估算了膳食暴露量。香港人膳食中多溴二苯醚的平均和第 95 个百分位数暴露量分别为 1.34 和 2.90ngkg(-1)体重日(-1)。多溴二苯醚的主要膳食来源是“鱼、海鲜及其制品”,占总暴露量的 27.3%,其次是“肉、禽和野味及其制品”(20.7%)、“谷物及其制品”(15.9%)和“脂肪和油”(15.9%)。按照欧洲食品安全局(EFSA)的方法,对四个重要同系物(BDE-47、BDE-99、BDE-153 和 BDE-209)进行计算的暴露量大量裕度(MOE)(>2.5)表明,估计的膳食暴露量不太可能成为一个显著的健康问题。

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