Gong Yan, Wen Sheng, Zheng Chuangmu, Peng Xitian, Li Yonggang, Hu Dingjin, Peng Lijun
Institute of Quality Standards and Testing Technology for Agro-Products, Hubei Academy of Agriculture Science, Wuhan, 430064, Hubei, China.
Environ Sci Pollut Res Int. 2015 Jun;22(11):8349-58. doi: 10.1007/s11356-014-3940-2. Epub 2014 Dec 24.
Polybrominated diphenyl ethers (PBDEs) are one class of brominated flame retardants (BFRs). Although studies have reported the occurrence of PBDEs in freshwater fish species from several locations, to our best knowledge, there was no comprehensive data on PBDEs in foods of animal origin, such as pork, egg, and milk samples from interior areas of China, where pork and eggs are the major constituents of diet. The levels of PBDEs (BDE-28, 47, 99, 100, 153, 154, and 183) were determined in samples of animal-derived foods widely consumed by the population of Hubei in east-central China and the middle reaches of the Yangtze River. Two hundred six samples of animal-derived foods were randomly acquired in 17 sites of Hubei in 2010. The highest medium concentration of ∑7PBDEs was found in chicken eggs (0.191 ng/g wet weight (ww)), followed by duck eggs (0.176 ng/g ww), pork (0.050 ng/g ww), carps (0.047 ng/g ww), and cow milk (0.013 ng/g ww). The estimated dietary intake of Σ7PBDEs for a standard adult of 60 kg body weight based on medium and 95th percentile concentrations with consumption of animal-derived foods in Hubei province were 157.5 and 1960.3 pg/kg body weight/day, respectively. Chicken eggs (65.9 %) and pork (23.4 %) were the largest contributors to dietary intake of ∑7PBDEs through animal-derived foods. The same PBDE sources were exposed in Hubei province via principal component analysis (PCA), and the particular congener profile in samples of animal-derived foods revealed the possible exposure history of octa-BDEs and penta-BDEs in the local region. The large margins of exposure (MOE) calculated following the European Food Safety Authority (EFSA) approach for three important congeners, BDE-47, BDE-99, and BDE-153, indicated that the estimated dietary exposures were unlikely to be a significant health concern to in Hubei.
多溴二苯醚（PBDEs）是一类溴化阻燃剂（BFRs）。尽管已有研究报道在多个地点的淡水鱼类中检测到多溴二苯醚，但据我们所知，在中国内陆地区，猪肉、鸡蛋和牛奶等动物源性食品中多溴二苯醚的综合数据尚属空白，而猪肉和鸡蛋是当地饮食的主要组成部分。本研究测定了中国中东部湖北省及长江中游地区人群广泛消费的动物源性食品样本中多溴二苯醚（BDE - 28、47、99、100、153、154和183）的含量。2010年在湖北省17个地点随机采集了206份动物源性食品样本。结果发现，鸡蛋中∑7PBDEs的中位浓度最高（0.191纳克/克湿重），其次是鸭蛋（0.176纳克/克湿重）、猪肉（0.050纳克/克湿重）、鲤鱼（0.047纳克/克湿重）和牛奶（0.013纳克/克湿重）。基于湖北省动物源性食品的中位浓度和第95百分位数浓度，估算体重60千克的标准成年人通过食用这些食品摄入∑7PBDEs的量分别为157.5和1960.3皮克/千克体重/天。通过动物源性食品摄入的∑7PBDEs中，鸡蛋（65.9%）和猪肉（23.4%）的贡献最大。通过主成分分析（PCA）发现，湖北省动物源性食品样本中多溴二苯醚的来源相同，特定的同系物分布特征揭示了当地八溴二苯醚和五溴二苯醚可能的暴露历史。按照欧洲食品安全局（EFSA）的方法计算的三种重要同系物BDE - 47、BDE - 99和BDE - 153的暴露边际（MOE）表明，湖北省通过饮食摄入多溴二苯醚不太可能对健康构成重大威胁。
