Division of Nephrology, Department of Internal Medicine, National Hospital Organization Chiba-East Hospital, Japan.
J Am Soc Nephrol. 2013 Sep;24(9):1493-502. doi: 10.1681/ASN.2012080831. Epub 2013 Jul 25.
It is unknown whether regular patient-doctor contact (PDC) contributes to better outcomes for patients undergoing hemodialysis. Here, we analyzed the associations between frequency and duration of PDC during hemodialysis treatments with clinical outcomes among 24,498 patients from 778 facilities in the international Dialysis Outcomes and Practice Patterns Study (DOPPS). The typical facility PDC frequency, estimated by facility personnel, was high (more than once per week) for 55% of facilities, intermediate (once per week) for 24%, and low (less than once per week) for 21%. The mean ± SD estimated duration of a typical interaction between patient and physician was 7.7 ± 5.6 minutes. PDC frequency and duration varied across DOPPS phases and countries; the proportion of facilities with high PDC frequency was 17% in the United States and 73% across the other countries. Compared with high PDC frequency, the adjusted hazard ratio (HR) for all-cause mortality was 1.06 (95% confidence interval [CI], 0.96 to 1.17) for intermediate PDC frequency and 1.11 (95% CI, 1.01 to 1.23) for low PDC frequency (P=0.03 for trend). Furthermore, each 5-minutes-shorter duration of PDC was associated with a 5% higher risk for death, on average (HR, 1.05; 95% CI, 1.01 to 1.09), adjusted for PDC frequency and other covariates. Multivariable analyses also suggested modest inverse associations between both PDC frequency and duration with hospitalization but not with kidney transplantation. Taken together, these results suggest that policies supporting more frequent and longer duration of PDC may improve patient outcomes in hemodialysis.
目前尚不清楚定期的医患接触(PDC)是否有助于接受血液透析的患者获得更好的治疗效果。在这里,我们分析了国际透析结果和实践模式研究(DOPPS)中来自 778 个医疗机构的 24498 名患者的 PDC 频率和时间与临床结果之间的关系。由医疗机构人员估计的典型医疗机构 PDC 频率,55%的医疗机构为高(每周一次以上),24%为中(每周一次),21%为低(每周一次以下)。患者与医生之间典型互动的平均估计持续时间为 7.7±5.6 分钟。PDC 频率和持续时间在 DOPPS 各阶段和国家之间存在差异;在美国,高 PDC 频率的医疗机构比例为 17%,而在其他国家则为 73%。与高 PDC 频率相比,中 PDC 频率的调整后全因死亡率的危险比(HR)为 1.06(95%置信区间[CI],0.96 至 1.17),低 PDC 频率的调整后 HR 为 1.11(95% CI,1.01 至 1.23)(趋势检验 P=0.03)。此外,平均而言,PDC 每次缩短 5 分钟,死亡风险增加 5%(HR,1.05;95% CI,1.01 至 1.09),校正了 PDC 频率和其他协变量。多变量分析还表明,PDC 频率和时间与住院治疗之间存在适度的反比关系,但与肾移植无关。综上所述,这些结果表明,支持更频繁和更长时间的 PDC 的政策可能会改善血液透析患者的治疗效果。