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血液透析患者的医护就诊频次与患者结局的相关性研究。

Association of provider-patient visit frequency and patient outcomes on hemodialysis.

机构信息

Veterans Administration Health Care System, Minneapolis, Minnesota, USA.

出版信息

J Am Soc Nephrol. 2012 Sep;23(9):1560-7. doi: 10.1681/ASN.2012010051. Epub 2012 Jul 12.

Abstract

In January of 2004, the Centers for Medicare & Medicaid Services tied provider reimbursement for outpatient hemodialysis services to the number of provider-patient visits per month. We aimed to determine whether greater visit frequency associated with lower mortality and hospitalization rates among incident hemodialysis patients in a large, nationally representative contemporary cohort. Using US Renal Data System data for 130,892 patients who initiated in-center hemodialysis between October 1, 2003 and September 30, 2006, we determined associations between the frequency of provider visits and mortality, first hospitalization, multiple hospitalizations, and cause-specific hospitalizations. Our primary analysis used Cox proportional hazards models, but we also performed time-varying Cox proportional hazards and instrumental variable analyses. In the primary analysis, we did not detect a significance difference in mortality among patients with four provider visits per month compared with those patients with fewer provider visits (adjusted HR=0.98; 95% CI=0.96-1.01), but the risk for first hospitalization was 4% lower among those patients with more frequent visits (adjusted HR=0.96; 95% CI=0.95-0.97). The time-varying Cox analysis produced similar results. The fully adjusted instrumental variable analysis showed a 0.07% higher risk for death that was not statistically significant (P=0.88) but a significant 2.3% lower risk for first hospitalization (P=0.001) for patients with four provider visits per month. In summary, greater frequency of provider visits to hemodialysis patients associates with a small but significant reduction in hospitalizations, but it does not consistently associate with lower risk for death.

摘要

2004 年 1 月,医疗保险和医疗补助服务中心(Centers for Medicare & Medicaid Services)将门诊血液透析服务的提供者报销与每月提供者-患者就诊次数挂钩。我们旨在确定在一个大型的、具有全国代表性的当代队列中,更多的就诊频率是否与新开始血液透析的患者的死亡率和住院率降低相关。使用美国肾脏数据系统(US Renal Data System)在 2003 年 10 月 1 日至 2006 年 9 月 30 日期间在中心开始血液透析的 130892 名患者的数据,我们确定了提供者就诊频率与死亡率、首次住院、多次住院和特定原因住院之间的关联。我们的主要分析使用了 Cox 比例风险模型,但我们也进行了时变 Cox 比例风险和工具变量分析。在主要分析中,我们没有发现每月就诊四次的患者与就诊次数较少的患者相比,死亡率有显著差异(调整后的 HR=0.98;95%CI=0.96-1.01),但就诊次数较多的患者首次住院的风险降低了 4%(调整后的 HR=0.96;95%CI=0.95-0.97)。时变 Cox 分析得出了类似的结果。完全调整后的工具变量分析显示,死亡风险增加了 0.07%,但没有统计学意义(P=0.88),而首次住院的风险降低了 2.3%,有统计学意义(P=0.001),每月就诊四次的患者。总之,增加血液透析患者的就诊频率与住院率的小但显著降低相关,但并不始终与死亡率降低相关。

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