Rollins School of Public Health, Emory University, Atlanta, GA 30309, USA.
Ann Epidemiol. 2012 Feb;22(2):104-11. doi: 10.1016/j.annepidem.2011.10.009. Epub 2011 Nov 21.
To examine associations between racial discrimination, mood disorders, and cardiovascular disease (CVD) among Black Americans.
Weighted logistic regression analyses were performed on a nationally representative sample of Black Americans (n = 5022) in the National Survey of American Life (NSAL; 2001-2003). Racial discrimination and CVD were assessed via self-report. Mood disorder was measured with the World Health Organization Composite International Diagnostic Interview.
Model-adjusted risk ratios (RRs) revealed that participants with a history of mood disorder had greater risk of CVD (RR, 1.28; 95% confidence interval (CI), 1.12-1.45). This relationship was found specifically among those younger than 50 years of age (RR, 1.56; 95% CI, 1.27-1.91). There was a significant interaction between racial discrimination and mood disorder in predicting CVD in the total (F = 2.86, 3 df, p = .047) and younger sample (F = 2.98, 3 df, p = .047). Participants with a history of mood disorder who reported high levels of racial discrimination had the greatest risk of CVD.
The association between racial discrimination and CVD is moderated by history of mood disorder. Future studies may examine pathways through which racial discrimination and mood disorders impact CVD risk among Black Americans.
探讨美国黑人中种族歧视、情绪障碍与心血管疾病（CVD）之间的关联。
对美国国家生活调查（NSAL；2001-2003 年）中具有代表性的 5022 名美国黑人样本进行加权逻辑回归分析。通过自我报告评估种族歧视和 CVD，通过世界卫生组织复合国际诊断访谈评估情绪障碍。
模型调整后的风险比（RR）显示，有情绪障碍史的参与者患 CVD 的风险更高（RR，1.28；95%置信区间（CI），1.12-1.45）。这一关系仅在年龄小于 50 岁的人群中发现（RR，1.56；95%CI，1.27-1.91）。在预测总样本（F=2.86，3df，p=0.047）和年轻样本（F=2.98，3df，p=0.047）中，种族歧视和情绪障碍在预测 CVD 方面存在显著交互作用。在报告有高水平种族歧视的有情绪障碍史的参与者中，CVD 的风险最高。
种族歧视与 CVD 之间的关联受情绪障碍史的调节。未来的研究可能会研究种族歧视和情绪障碍影响美国黑人 CVD 风险的途径。
