Division of Rheumatology, Johns Hopkins University School of Medicine, 1830 East Monument St Suite 7500, Baltimore, MD 21205, USA.
Curr Rheumatol Rep. 2013 Sep;15(9):360. doi: 10.1007/s11926-013-0360-0.
The Hopkins lupus cohort is a longitudinal cohort study of over 2,000 systemic lupus erythematosus (SLE) patients, who are seen quarterly. This review covers ten important clinically-relevant studies of the cohort. These studies include the function of prednisone in atherosclerosis and thrombosis, the preventive function of hydroxychloroquine, new insights into rare neurological manifestations, and treatment of flares with bursts of steroids rather than maintenance steroids.
霍普金斯狼疮队列是一项针对超过 2000 名系统性红斑狼疮 (SLE) 患者的纵向队列研究,这些患者每季度接受一次检查。本综述涵盖了该队列的 10 项重要临床相关研究。这些研究包括泼尼松在动脉粥样硬化和血栓形成中的作用、羟氯喹的预防作用、罕见神经表现的新见解,以及用类固醇爆发而不是维持类固醇治疗发作。