Edery M, Turner T, Dauder S, Young G, Bern H A
Unité d'Endocrinologie Moléculaire, INRA, Jouy-en-Josas, France.
Proc Soc Exp Biol Med. 1990 Sep;194(4):289-92. doi: 10.3181/00379727-194-43093.
Neonatal exposure to the synthetic estrogen, diethylstilbestrol, is known to affect the structure of the male reproductive system; thus, changes may also occur in the levels of hormone receptors. Prolactin receptor levels from the reproductive systems of male BALB/c mice exposed neonatally to diethylstilbestrol were analyzed. Neonatal exposure to diethylstilbestrol caused significant decreases (i) in prolactin receptor levels in the seminal vesicle, ductus deferens, and anterior and ventral prostates and (ii) in tissue weight and protein content in reproductive organs other than the ventral prostate.
已知新生儿接触合成雌激素己烯雌酚会影响雄性生殖系统的结构；因此，激素受体水平也可能发生变化。分析了新生期接触己烯雌酚的雄性BALB/c小鼠生殖系统中的催乳素受体水平。新生期接触己烯雌酚导致（i）精囊、输精管以及前列腺前叶和腹叶中的催乳素受体水平显著降低，以及（ii）除腹叶前列腺外的生殖器官的组织重量和蛋白质含量显著降低。
