Biochemical properties of mammalian DNA ligase I and the molecular defect in Bloom's syndrome.
作者信息
Tomkinson A E, Lasko D D, Lindahl T
机构信息
Imperial Cancer Research Fund, South Mimms, Herts, U.K.
出版信息
Prog Clin Biol Res. 1990;340A:283-94.
PMID:2388916
Abstract
摘要
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DNA ligase I variants fail in the ligation of mutagenic repair intermediates with mismatches and oxidative DNA damage.DNA 连接酶 I 变体在连接具有错配和氧化 DNA 损伤的诱变修复中间体方面失效。
Mutagenesis. 2020 Dec 1;35(5):391-404. doi: 10.1093/mutage/geaa023.
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