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采用五种不同问卷评估哮喘控制:一项前瞻性研究。

Asthma control measurement using five different questionnaires: a prospective study.

机构信息

Chest Service, CHU Saint-Pierre, Rue Haute 322, 1000 Brussels, Belgium.

出版信息

Respir Med. 2013 Sep;107(9):1314-21. doi: 10.1016/j.rmed.2013.07.003. Epub 2013 Jul 26.

DOI:10.1016/j.rmed.2013.07.003
PMID:23890766
Abstract

UNLABELLED

Questionnaires play a key place in the assessment of asthma control. Different questionnaires have been developed. However, it remains largely unknown whether they can be used interchangeably. We wondered whether the panel of frequently used scores would give similar measurement of asthma control. The present study aimed to assess the agreement between five specific questionnaires.

METHODS

In this prospective study, ninety-nine patients completed five commonly used asthma control scores: the GINA, the Asthma Control Test™, the Royal College of Physician score, the Asthma Therapy Assessment Questionnaire (ATAQ), and the Asthma Control Questionnaire(©) (ACQ). The kappa coefficient was used to assess the agreement between questionnaires.

RESULTS

The agreement between the GINA and other scores was only moderate (kappa coefficients amounted from 0.41 to 0.60). With respect to the "controlled" level, all the other scores gave higher results than GINA. All other scores also tended to underestimate GINA "uncontrolled level". For the "partly controlled level" defined by 3 of the 5 questionnaires, ACQ identified the same percentage of patients than GINA while ATAQ overestimated this percentage.

CONCLUSION

This study shows only moderate agreement between five commonly used asthma control scores. The GINA score showed the lowest percentage of controlled and the highest percentage of uncontrolled asthma. As a consequence, all these scores do not seem to evaluate the same symptoms.

TRIAL REGISTRATION NUMBER

NCT01350661.

摘要

未标注

问卷在评估哮喘控制方面起着关键作用。已经开发出不同的问卷。然而,它们是否可以互换使用在很大程度上仍然未知。我们想知道常用评分是否可以给出相似的哮喘控制测量。本研究旨在评估五种常用问卷之间的一致性。

方法

在这项前瞻性研究中,99 名患者完成了五个常用的哮喘控制评分:GINA、哮喘控制测试™、皇家内科医师学院评分、哮喘治疗评估问卷(ATAQ)和哮喘控制问卷(ACQ)。使用 Kappa 系数评估问卷之间的一致性。

结果

GINA 与其他评分之间的一致性仅为中度(kappa 系数从 0.41 到 0.60)。关于“控制”水平,所有其他评分都高于 GINA。所有其他评分也倾向于低估 GINA 的“未控制”水平。对于 5 个问卷中的 3 个定义的“部分控制”水平,ACQ 确定的患者比例与 GINA 相同,而 ATAQ 则高估了这一比例。

结论

本研究仅显示五种常用哮喘控制评分之间存在中度一致性。GINA 评分显示控制哮喘的比例最低,未控制哮喘的比例最高。因此,这些评分似乎并没有评估相同的症状。

试验注册号

NCT01350661。

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