Department of Cardiology, Queen Elizabeth Hospital, Woodville South, SA, Australia.
Am J Emerg Med. 2013 Nov;31(11):1627.e1-4. doi: 10.1016/j.ajem.2013.06.039. Epub 2013 Jul 26.
Takotsubo cardiomyopathy (TTC) is a well-known condition, which leads to sudden transient regional systolic dysfunction. It mostly affects aging women and is usually precipitated by emotional or physical stress. Despite the tremendous amount of literature on TTC, cardiac sympathetic hyperactivity is the only thing known to be associated with pathogenesis. In our case, an elderly woman presented with an acute episode of TTC 24 hours after anti-influenza vaccination without any obvious stressor for sudden rise in the catecholamine level. Sudden postvaccination change in the cardiac sympathetic discharge is the most likely precipitant of TTC in this case.
心尖球形综合征（TTC）是一种广为人知的病症，会导致突发性短暂区域性收缩功能障碍。它主要影响老年女性，通常由情绪或身体压力引发。尽管有大量关于 TTC 的文献，但目前仅发现心脏交感神经活性亢进与发病机制有关。在我们的病例中，一位老年女性在接种流感疫苗后 24 小时出现急性 TTC 发作，没有明显的应激源导致儿茶酚胺水平突然升高。在这种情况下，接种疫苗后心脏交感神经放电的突然变化很可能是 TTC 的诱因。
