School of Marine and Tropical Biology, James Cook University, Townsville, Queensland 4811, Australia.
Aquat Toxicol. 2013 Sep 15;140-141:337-9. doi: 10.1016/j.aquatox.2013.06.021. Epub 2013 Jul 4.
Cholinesterase activity usually decreases in fish exposed to anticholinesterase compounds such as organophosphate and carbamate pesticides. Here we show that tropical reef fish Acanthochromis polyacanthus (or spiny damsel) also exhibits a decrease in ChE activity when exposed to elevated temperature from 28°C to 32°C or 34°C after 4 days. We further demonstrate that the decline persists even after 7 days of recovery at control temperature. This is the first report of a drop in ChE activity in fish as temperature increases. Our results strongly suggest the need for long-term monitoring of water temperature in the field prior to sampling A. polyacanthus for toxicology studies, as temperature is a prolonged and confounding factor for ChE activity in this species.
当鱼类暴露于有机磷和氨基甲酸酯等拟除虫菊酯化合物时，其胆碱酯酶活性通常会降低。在这里，我们表明，热带珊瑚礁鱼棘尾鱼（或刺尾鱼）在暴露于升高的温度（4 天后从 28°C 升高到 32°C 或 34°C）后，ChE 活性也会降低。我们进一步证明，即使在控制温度下恢复 7 天后，这种下降仍然存在。这是鱼类的 ChE 活性随温度升高而下降的首例报道。我们的研究结果强烈表明，在对棘尾鱼进行毒理学研究之前，需要在野外对水温进行长期监测，因为温度是该物种 ChE 活性的一个长期且复杂的因素。
