Kuznetsov S V, Kim I S, Ananchenko V G
Sov Med. 1990(5):25-8.
Cytochemistry of peripheral blood lymphocyte enzymes was studied in 58 patients with State II essential hypertension (36 of these were treated with traditional hypotensive therapy and 22 with plasmapheresis + drug therapy). alpha-GPDH, LDH, and acid phosphatase activities were found reduced in these patients. The degree of the enzymic activity reduction (SDH included) depended on the disease standing and family history of patients. Plasmapheresis elevated the activities of energy enzymes and reduced arterial pressure, i.e. these parameters were in inverse correlation. In the patients treated by routine hypotensive therapy energy enzymes' activity was unchanged, despite the clinical effect.
对58例Ⅱ期原发性高血压患者（其中36例接受传统降压治疗，22例接受血浆置换+药物治疗）的外周血淋巴细胞酶进行了细胞化学研究。发现这些患者的α-甘油磷酸脱氢酶、乳酸脱氢酶和酸性磷酸酶活性降低。酶活性降低的程度（包括琥珀酸脱氢酶）取决于患者的病情和家族史。血浆置换提高了能量酶的活性并降低了动脉血压，即这些参数呈负相关。在接受常规降压治疗的患者中，尽管有临床效果，但能量酶的活性没有变化。
