Leishmania infecting man and wild animals in Saudi Arabia. 7. Partial protection of mice against Leishmania major by prior infection with L. arabica.
作者信息
Neal R A, Reeves A, Peters W
机构信息
Department of Medical Parasitology, London School of Hygiene and Tropical Medicine, UK.
出版信息
Trans R Soc Trop Med Hyg. 1990 Mar-Apr;84(2):233-8. doi: 10.1016/0035-9203(90)90267-i.
PMID:2389313
Abstract
A survey of inbred mouse strains showed that strain C3H/he was the most comparable to man in respect of its susceptibility to Leishmania major and the subsequent healing of lesions produced by this organism. L. arabica proved to have a lower virulence than L. major and prior inoculation with the former resulted in a decrease of the lesion sizes following subsequent L. major challenge. Moreover, L. major lesions that did develop in mice previously inoculated with L. arabica generally healed faster.
摘要
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