Neal R A, Reeves A, Peters W
Department of Medical Parasitology, London School of Hygiene and Tropical Medicine, UK.
Trans R Soc Trop Med Hyg. 1990 Mar-Apr;84(2):233-8. doi: 10.1016/0035-9203(90)90267-i.
A survey of inbred mouse strains showed that strain C3H/he was the most comparable to man in respect of its susceptibility to Leishmania major and the subsequent healing of lesions produced by this organism. L. arabica proved to have a lower virulence than L. major and prior inoculation with the former resulted in a decrease of the lesion sizes following subsequent L. major challenge. Moreover, L. major lesions that did develop in mice previously inoculated with L. arabica generally healed faster.
对近交系小鼠品系的一项调查显示，就其对硕大利什曼原虫的易感性以及该生物体产生的病变随后的愈合情况而言，C3H/he品系与人类最为相似。阿拉伯利什曼原虫的毒力被证明低于硕大利什曼原虫，预先接种前者会导致随后受到硕大利什曼原虫攻击后病变大小减小。此外，先前接种过阿拉伯利什曼原虫的小鼠中确实出现的硕大利什曼原虫病变通常愈合得更快。
