National Center for STD Control, and the Chinese Academy of Medical Sciences and Peking Union Medical College Institute of Dermatology, Nanjing, China.
PLoS One. 2013 Jul 22;8(7):e69697. doi: 10.1371/journal.pone.0069697. Print 2013.
To determine seropositivity of herpes simplex virus type 2 (HSV-2) infection and associated risk factors among female sex workers (FSWs) in Guangxi, China.
A convenience sample of FSWs was recruited from different types of sex work venues in two cities (Wuzhou and Hezhou) in Guangxi. Blood specimens were collected for ELISA-based detection of HSV-2 antibodies to examine the seropositivity of HSV-2 infection. Socio-demographic and behavioral data were collected through a structured questionnaire interview. Association of HSV-2 seropositivity with socio-demographic and behavioral characteristics and HIV status was analyzed.
The overall prevalence of HSV-2 seropositivity among 2453 FSWs was 54.9% (95% confidence interval [CI], 52.9-56.9%). The HSV-2 seropositivity was independently associated with older age, low education level, non-Han minority, migration status, working in lower-tier venues and positive HIV status.
The study indicates a high prevalence of HSV-2 infection among FSWs, particularly in those working in low-tier venues in study areas, suggesting the needs to further emphasize the inclusion of HSV-2 in surveillance and intervention programs in this population.
在中国广西，确定女性性工作者（FSW）中单纯疱疹病毒 2 型（HSV-2）感染的血清阳性率及其相关危险因素。
从广西两个城市（梧州和贺州）不同类型的性工作场所中抽取方便样本，采集 FSW 的血样，进行基于酶联免疫吸附试验的 HSV-2 抗体检测，以检查 HSV-2 感染的血清阳性率。通过结构化问卷访谈收集社会人口统计学和行为数据。分析 HSV-2 血清阳性率与社会人口统计学和行为特征以及 HIV 状况的关联。
在 2453 名 FSW 中，HSV-2 血清阳性率总体为 54.9%（95%置信区间[CI]，52.9-56.9%）。HSV-2 血清阳性率与年龄较大、教育程度较低、非汉族、流动人口身份、在低级别场所工作以及 HIV 阳性状况独立相关。
本研究表明 FSW 中 HSV-2 感染率较高，尤其是在研究地区低级别场所工作的 FSW 中，这表明需要进一步强调将 HSV-2 纳入该人群的监测和干预计划中。
