Zhang Qian-Qian, Cheng Jun-Zhen, Wang Feng-Hui
Medical College of Yan'an University, Yan'an 716000, China.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2013 Apr;25(2):209-10.
To understand the correlation between TORCH infections and adverse pregnancy outcomes, so as to provide recommendations for birth defect interventions.
The serum samples from 900 pregnant women were tested for TORCH-IgM by capture ELISA. The women with positive results were followed up and the outcomes of their pregnancies were investigated.
The total TORCH-IgM positive rate of the pregnant women was 4.11% (37/900). The IgM positive rates of CMV, HSV II , RV and TOX were 2.00% (18/900), 0.78% (7/900), 0.44% (4/900), and 0.89% (8/900) respectively. Thirty-one TORCH-IgM positive pregnant women continued their pregnancies and 20 of them were found abnormal pregnancy outcomes, accounting for 64.52%.
TORCH infections are important risk factors responsible for abnormal pregnant outcomes. The screening of TORCH should be performed during pregnancy, and the appropriate interventions can reduce the occurrence of abnormal pregnancy and prevent birth defects.
了解TORCH感染与不良妊娠结局之间的相关性，以便为出生缺陷干预提供建议。
采用捕获ELISA法对900例孕妇血清样本进行TORCH-IgM检测。对检测结果为阳性的孕妇进行随访，调查其妊娠结局。
孕妇TORCH-IgM总阳性率为4.11%（37/900）。CMV、HSV II、RV和TOX的IgM阳性率分别为2.00%（18/900）、0.78%（7/900）、0.44%（4/900）和0.89%（8/900）。31例TORCH-IgM阳性孕妇继续妊娠，其中20例出现异常妊娠结局，占64.52%。
TORCH感染是导致妊娠异常结局的重要危险因素。孕期应进行TORCH筛查，采取适当干预措施可减少异常妊娠的发生，预防出生缺陷。
