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脱发组织病理学评估的当前进展:二合一还是一分为二?

The current state of play in the histopathologic assessment of alopecia: two for one or one for two?

作者信息

Tailor Ameet, Asher Ruth G, Craig Paul J, Groves Richard W, Fenton David A, Stefanato Catherine M

机构信息

Department of Dermatopathology, St. Thomas' Hospital, London, UK.

出版信息

J Cutan Pathol. 2013 Mar;40(3):298-304. doi: 10.1111/cup.12075.

DOI:10.1111/cup.12075
PMID:23899265
Abstract

The histopathologic assessment of a scalp biopsy for alopecia relies largely on the quality of the specimen provided for evaluation. There are a number of different protocols in the literature which have been proposed over the years, but no consensus has yet been reached as to the appropriate number of biopsies to be taken, or to which sectioning technique is the gold standard for achieving the best diagnostic yield. We herein review the pros and cons of the various protocols and share the experience with our St John's protocol.

摘要

对头皮活检进行组织病理学评估以诊断脱发,很大程度上依赖于提供用于评估的标本质量。多年来,文献中提出了许多不同的方案,但对于应进行活检的合适数量,或者哪种切片技术是获得最佳诊断结果的金标准,尚未达成共识。我们在此回顾各种方案的优缺点,并分享我们采用圣约翰方案的经验。

相似文献

1
The current state of play in the histopathologic assessment of alopecia: two for one or one for two?脱发组织病理学评估的当前进展:二合一还是一分为二?
J Cutan Pathol. 2013 Mar;40(3):298-304. doi: 10.1111/cup.12075.
2
The modified HoVert (mHoVert) method improves diagnostic certainty compared to the St John's protocol for alopecia biopsy specimens: A retrospective single center study.改良 HoVert(mHoVert)法与圣约翰协议相比,可提高脱发活检标本的诊断确定性:一项回顾性单中心研究。
J Cutan Pathol. 2023 Dec;50(12):1099-1103. doi: 10.1111/cup.14447. Epub 2023 May 19.
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Is more hair always better? A single biopsy specimen is preferred for the evaluation of alopecia.头发越多就越好吗?对于脱发评估,单个活检标本更佳。
J Cutan Pathol. 2014 Jan;41(1):66-7. doi: 10.1111/cup.12228. Epub 2013 Oct 7.
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A study of serial vertical sectioning of scalp biopsies to increase the histological diagnostic yield in alopecias.一项关于头皮活检连续垂直切片的研究,以提高脱发症的组织学诊断率。
J Eur Acad Dermatol Venereol. 2010 Jun;24(6):709-15. doi: 10.1111/j.1468-3083.2009.03499.x. Epub 2009 Nov 23.
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Vertical vs. transverse sections of scalp biopsy specimens: a pilot study on the comparison of the diagnostic value of two techniques in alopecia.头皮活检标本的纵切面与横切面:两种技术在脱发诊断价值比较中的初步研究。
Clin Exp Dermatol. 2011 Dec;36(8):855-63. doi: 10.1111/j.1365-2230.2011.04154.x. Epub 2011 Sep 15.
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Cicatricial alopecia: classification and histopathology.瘢痕性脱发:分类与组织病理学
Dermatol Ther. 2008 Jul-Aug;21(4):221-37. doi: 10.1111/j.1529-8019.2008.00203.x.
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The histopathology of noncicatricial alopecia.非瘢痕性脱发的组织病理学
Semin Cutan Med Surg. 2006 Mar;25(1):35-40. doi: 10.1016/j.sder.2006.01.005.
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The HoVert technique: a novel method for the sectioning of alopecia biopsies.HoVert技术:一种用于切片斑秃活检组织的新方法。
J Cutan Pathol. 2011 May;38(5):401-6. doi: 10.1111/j.1600-0560.2010.01669.x. Epub 2011 Jan 19.
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Alopecia: histologic diagnosis by transverse sections.脱发:通过横切面进行组织学诊断。
Semin Diagn Pathol. 1996 Feb;13(1):2-18.
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The transversely sectioned scalp biopsy specimen: the technique and an algorithm for its use in the diagnosis of alopecia.经横向切片的头皮活检标本:其技术及用于斑秃诊断的算法。
Adv Dermatol. 1994;9:127-57; discussion 158.

引用本文的文献

1
Utility of horizontal and vertical sections of scalp biopsies in various forms of primary alopecias.头皮活检水平及垂直切片在各种原发性脱发形式中的应用价值。
J Lab Physicians. 2018 Jan-Mar;10(1):95-100. doi: 10.4103/JLP.JLP_4_17.