Eudy Grant, Solomon Alvin R
Department of Dermatolog, Emory University School of Medicine, Atlanta, GA 30322, USA.
Semin Cutan Med Surg. 2006 Mar;25(1):35-40. doi: 10.1016/j.sder.2006.01.005.
During the past 2 decades, the use of transverse sections in the evaluation of scalp biopsy specimens has led to a better understanding of the histopathologic changes in both cicatricial and noncicatricial alopecia. However, the technique has provided the most significant gains in the study of the latter type of alopecia, where evaluation of follicle density and follicular dynamics are integral to accurate diagnosis. This report reviews the histopathologic findings of four common types of noncicatricial alopecia: androgenetic alopecia, telogen effluvium, alopecia areata, and trichotillomania/chronic traction alopecia.
在过去20年里,在头皮活检标本评估中使用横断面已使人们对瘢痕性和非瘢痕性脱发的组织病理学变化有了更好的理解。然而,该技术在研究后一种类型的脱发方面取得了最为显著的进展,在这种脱发类型中,毛囊密度和毛囊动态评估对于准确诊断至关重要。本报告回顾了四种常见非瘢痕性脱发的组织病理学发现:雄激素性脱发、休止期脱发、斑秃和拔毛癖/慢性牵拉性脱发。