Linn Rebecca L, Kiley Jessica, Minturn Lucy, Fritsch Michael K, Dejulio Todd, Rostlund Emily, Ernst Linda M
1 Department of Pathology, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Pediatr Dev Pathol. 2013 Sep-Oct;16(5):378-86. doi: 10.2350/13-06-1351-CR.1. Epub 2013 Jul 30.
Massive perivillous fibrin deposition (MPVFD) of the placenta and renal tubular dysgenesis (RTD) are relatively rare diseases with potential recurrent risks that have not previously associated in the literature. Herein, we report the clinical course, autopsy findings, and placental pathologic features from 3 consecutive pregnancies delivered in 1 woman, all showing recurrent MPVFD in the placenta and RTD in the bilateral fetal kidneys.
胎盘大量绒毛周围纤维蛋白沉积(MPVFD)和肾小管发育不全(RTD)是相对罕见的疾病,具有潜在的复发风险,此前文献中未有相关关联报道。在此,我们报告了一名女性连续3次妊娠的临床过程、尸检结果及胎盘病理特征,所有病例均显示胎盘复发性MPVFD及双侧胎儿肾脏RTD。