Benavides Olga, Alburquerque Daniela, Chaná-Cuevas Pedro
Centro de Trastornos del Movimiento, Facultad de Ciencias Médicas, Universidad de Santiago de Chile, Santiago, Chile.
Rev Med Chil. 2013 Mar;141(3):320-6. doi: 10.4067/S0034-98872013000300006.
Parkinson disease (EPI) patients often require being assisted by others. These caregivers are exposed to a decrease in their quality of Ufe.
To explore Parkinson disease patient features associated with a greater burden among their caregivers.
Fifty one patients with Parkinson disease (aged 67 ± 12 years, 29 men, with 8 ± 5 years of disease) and their caregivers, were studied. Patients were assessed with the Unified Parkinson Disease Rating Scale III, the Hoehn & Yahr stage standardization, Parkinson s minimental test, the neuropsychiatric inventory and the Beck Depression Inventory (IDB). The Zarit Burden Interview (ESZ) was applied to caregivers.
According to IDB, 45% of patients whose caregivers presented little or no burden had a depression, compared to 78% of those whose caregivers had modérate or intense burden. (p < 0.01). The ESZ score of caregivers correlated significantly with Parkinson patients' age, IDB and axial involvement in the UPDRS-III (correlation coefficients ofOAp < 0.01, 0.6p < 0.01 and 0.46 p < 0.01, respectively).
Motor alterations, cognitive impairment and most importantly depression of patients with Parkinson disease are deteminants of burden for their caregivers.
帕金森病（EPI）患者常常需要他人照料。这些照料者的生活质量会下降。
探究与照料者负担较重相关的帕金森病患者特征。
对51例帕金森病患者（年龄67±12岁，男性29例，病程8±5年）及其照料者进行研究。采用统一帕金森病评定量表III、霍恩和雅尔分期标准、帕金森简易精神状态检查、神经精神量表和贝克抑郁量表（IDB）对患者进行评估。对照料者应用扎里特负担访谈量表（ESZ）。
根据IDB，照料者负担较轻或无负担的患者中，45%存在抑郁，而照料者负担中等或较重的患者中，这一比例为78%。（p<0.01）。照料者的ESZ评分与帕金森病患者的年龄、IDB以及统一帕金森病评定量表III中的轴性受累情况显著相关（相关系数分别为0.4，p<0.01；0.6，p<0.01；0.46，p<0.01）。
帕金森病患者的运动改变、认知障碍，最重要的是抑郁，是其照料者负担的决定因素。
