[智利帕金森病死亡率]

[Parkinson disease mortality rates in Chile].

作者信息

Chaná C Pedro, Jiménez C Magdalena, Díaz T Violeta, Juri Carlos

机构信息

Centro de Trastornos del Movimiento, Universidad de Santiago de Chile, Santiago, Chile.

出版信息

Rev Med Chil. 2013 Mar;141(3):327-31. doi: 10.4067/S0034-98872013000300007.

DOI:10.4067/S0034-98872013000300007

PMID:23900323

Abstract

BACKGROUND

Parkinson disease (PD) is the second more common neurodegenerative disorder and determines a loss in quality of life, caregiver burden and increased mortality in those affected.

AIM

To determine the rates of mortality due to Parkinson disease in Chile.

MATERIAL AND METHODS

Data were collected from death certificates between 1997 and 2008. Mortality rates were calculated and the mortality trend was established along the study period, and analyzed by age, sex and geographic región of Chile.

RESULTS

There was a steady increase in mortality over the years, particularly since 2001 (r²= 0.85, p < 0.01). The increase in mortality rates was 0.25 per 100.000 habitants/year (r²: 0.89, p < 0.01). Mortality was always higher in men and in those older than 80 years. The highest rate (per 100,000 habitants) in Chile was observed in the región of Valparaíso (2.4) while the lowest was in Antofagasta (0.8) (t = 3.72, p < 0.05).

CONCLUSIONS

Mortality associated with PD has increased progressively, consistent with the expected increase in prevalence of the disease in the population.

摘要

背景

帕金森病（PD）是第二常见的神经退行性疾病，会导致患者生活质量下降、照料者负担加重以及死亡率上升。

目的

确定智利帕金森病的死亡率。

材料与方法

收集了1997年至2008年期间死亡证明的数据。计算了死亡率，并确定了整个研究期间的死亡趋势，并按年龄、性别和智利的地理区域进行了分析。

结果

多年来死亡率稳步上升，尤其是自2001年以来（r² = 0.85，p < 0.01）。死亡率每年每10万居民增加0.25（r²：0.89，p < 0.01）。男性和80岁以上人群的死亡率一直较高。智利瓦尔帕莱索地区的死亡率最高（每10万居民）（2.4），而最低的是安托法加斯塔（0.8）（t = 3.72，p < 0.05）。