Department of Anesthesiology, First Affiliated Hospital of Wenzhou Medical College, Wenzhou, Zhejiang, People's Republic of China.
Ther Clin Risk Manag. 2013;9:299-302. doi: 10.2147/TCRM.S45053. Epub 2013 Jul 23.
To compare the clinical effects of anesthesia and postoperative analgesia for patients with unilateral lower-extremity fracture between multiple injections through catheters beside the lumbar plexus or sciatic nerve and continuous epidural analgesia.
Seventy patients with unilateral lower-extremity fracture scheduled for internal fixation were randomly divided into group N (n = 35) and group E (n = 35). Patients in group N received combined lumbar plexus and sciatic nerve block, then a catheter was inserted into the psoas compartment or beside the sciatic nerve, according to the surgical site, and 25 mL 0.375% ropivacaine was injected into patients in group N through the peripheral nerve catheter 12 hours after operation. Patients in group E received combined spinal and epidural anesthesia, and when the operation was complete kept the epidural catheter and received patient-controlled epidural analgesia with an analgesia pump.
The visual analog scores of patients at each time point in the two groups showed no significant difference (P > 0.05). Mean arterial pressure at 30 minutes after anesthesia and 4 hours postoperation in group E decreased significantly and was significantly lower than group N (P < 0.01). Group E had significantly higher rate of urinary retention than group N (P < 0.05), and the time of first food intake of patients in group N was significantly shorter than in group E (P < 0.001).
For patients with unilateral lower-extremity fracture receiving internal fixation, multiple injections through catheters beside the lumbar plexus or sciatic nerve can provide adequate postoperative analgesia, with very few adverse effects.
比较经腰椎丛或坐骨神经旁置管多次注射与连续硬膜外镇痛用于单侧下肢骨折患者麻醉和术后镇痛的临床效果。
70 例行内固定术的单侧下肢骨折患者随机分为 N 组(n=35)和 E 组(n=35)。N 组患者接受腰丛和坐骨神经联合阻滞,然后根据手术部位将导管插入腰大肌间隙或坐骨神经旁,术后 12 小时通过外周神经导管向 N 组患者注射 25 mL 0.375%罗哌卡因。E 组患者接受联合脊髓和硬膜外麻醉,手术完成后保留硬膜外导管,并使用镇痛泵行患者自控硬膜外镇痛。
两组患者各时间点的视觉模拟评分均无显著差异(P>0.05)。E 组患者麻醉后 30 分钟和术后 4 小时的平均动脉压显著降低,且显著低于 N 组(P<0.01)。E 组患者的尿潴留发生率显著高于 N 组(P<0.05),N 组患者的首次进食时间显著短于 E 组(P<0.001)。
对于行内固定术的单侧下肢骨折患者,经腰椎丛或坐骨神经旁置管多次注射可提供充分的术后镇痛,且不良反应极少。