Khan Mohammad Iqbal, Zafar Afsheen, Younas Maleeha, Malik Irfan
Department of Surgery, Azad Jammu and Kashmir Medical College, Muzaffaraabad.
J Pak Med Assoc. 2013 Jun;63(6):775-7.
Primary mesenteric liposarcoma is extremely rare and is treated by aggressive surgical management i.e. wide excision with adequate margins (in the absence of distant metastases). We report a case of huge slow-growing primary mesenteric liposarcoma in a 52-year-old man, who presented with gross abdominal distension. He was anaemic with pre-operative imaging demonstrating a well-encapsulated huge solid tumour filling the whole abdomen, abutting the anterior abdominal wall without any evidence of distance metastasis or ascites. The patient underwent successful resection of the tumour which weighed 22 kilograms. Histopathology confirmed a well-differentiated liposarcoma with rare mitoses. The patient received full eight cycles of adjuvant chemotherapy. After five years of clinical and imaging follow-up, there was no evidence of metastasis or recurrence of the disease.
原发性肠系膜脂肪肉瘤极为罕见，治疗方式为积极的手术处理，即广泛切除且切缘充分（无远处转移时）。我们报告一例52岁男性巨大、生长缓慢的原发性肠系膜脂肪肉瘤病例，患者表现为明显的腹部膨隆。他有贫血，术前影像学检查显示一个边界清晰的巨大实性肿瘤充满整个腹部，紧邻前腹壁，无远处转移或腹水迹象。患者成功切除了重达22千克的肿瘤。组织病理学证实为高分化脂肪肉瘤，有罕见的核分裂象。患者接受了完整的八个周期辅助化疗。经过五年的临床和影像学随访，无疾病转移或复发迹象。
