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Strong interplay between metabolic syndrome, obstructive sleep apnoea, oxidative stress and arterial dysfunction.

作者信息

Del Ben Maria, Loffredo Lorenzo, Violi Francesco, Angelico Francesco

机构信息

I Clinica Medica, Department of Internal Medicine, Sapienza University of Rome, Policlinico Umberto 1 Viale del Policlinico 155, 00161, Rome, Italy.

出版信息

Sleep Breath. 2014 May;18(2):223-4. doi: 10.1007/s11325-013-0882-8. Epub 2013 Aug 1.

DOI:10.1007/s11325-013-0882-8
PMID:23904242
Abstract
摘要

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Moderate weight loss decreases oxidative stress and increases antioxidant status in patients with metabolic syndrome.适度体重减轻可降低代谢综合征患者的氧化应激并提高抗氧化状态。
ISRN Obes. 2012 Nov 6;2012:960427. doi: 10.5402/2012/960427. eCollection 2012.
2
Endothelial function is well preserved in obese patients with mild obstructive sleep apnea.轻度阻塞性睡眠呼吸暂停的肥胖患者的内皮功能保存良好。
Sleep Breath. 2014 Mar;18(1):177-86. doi: 10.1007/s11325-013-0867-7. Epub 2013 Jun 4.
3
Oxidative stress mediated arterial dysfunction in patients with obstructive sleep apnoea and the effect of continuous positive airway pressure treatment.
阻塞性睡眠呼吸暂停患者的氧化应激介导的动脉功能障碍及持续气道正压通气治疗的影响。
BMC Pulm Med. 2012 Jul 23;12:36. doi: 10.1186/1471-2466-12-36.
4
Obesity and hypercholesterolemia are associated with NOX2 generated oxidative stress and arterial dysfunction.肥胖和高胆固醇血症与 NOX2 产生的氧化应激和动脉功能障碍有关。
J Pediatr. 2012 Dec;161(6):1004-9. doi: 10.1016/j.jpeds.2012.05.042. Epub 2012 Jun 23.
5
Weight loss is associated with improved endothelial dysfunction via NOX2-generated oxidative stress down-regulation in patients with the metabolic syndrome.在代谢综合征患者中，通过下调 NADPH 氧化酶 2 产生的氧化应激，体重减轻与改善内皮功能障碍有关。
Intern Emerg Med. 2012 Jun;7(3):219-27. doi: 10.1007/s11739-011-0591-x. Epub 2011 Apr 22.
6
Obstructive sleep apnoea syndrome and the metabolic syndrome in an internal medicine setting.内科环境中的阻塞性睡眠呼吸暂停综合征与代谢综合征。
Eur J Intern Med. 2010 Jun;21(3):191-5. doi: 10.1016/j.ejim.2010.03.006. Epub 2010 Mar 29.