Department of Nuclear Medicine, Rambam Health Care Campus, Haifa, Israel.
Semin Nucl Med. 2013 Sep;43(5):396-402. doi: 10.1053/j.semnuclmed.2013.04.004.
Graft infection following prosthetic vascular reconstruction is an uncommon but severe complication. The clinical presentation is often subtle and nonspecific and may occur long after surgery. Although defining a prosthetic vascular graft infection can be difficult, early diagnosis and treatment are essential for the correct choice of treatment to prevent further complications as well as the high morbidity and mortality associated with repeat surgery and removal of infected grafts. False-positive results may lead to unnecessary surgery while failure to diagnose graft infection may have life-threatening sequels. Scarce literature that is currently available regarding the role of (18)F-labeled fluorodeoxyglucose imaging for assessment of vascular graft infection suggests that this modality may represent reliable noninvasive imaging modality in this specific clinical setting. PET/CT increases the test specificity and thus improves diagnostic accuracy. The precise anatomic localization of increased (18)F-labeled fluorodeoxyglucose PET/CT enables accurate differentiation between graft and adjacent soft tissue infection leading to more accurate diagnosis and subsequent optimized therapeutic strategy.
人工血管重建术后移植物感染是一种不常见但严重的并发症。临床表现通常不明显且无特异性，可能在手术后很长时间才出现。尽管确定人工血管移植物感染可能具有挑战性，但早期诊断和治疗对于正确选择治疗方法至关重要，以防止进一步的并发症以及与重复手术和移除感染移植物相关的高发病率和死亡率。假阳性结果可能导致不必要的手术，而未能诊断移植物感染可能会产生危及生命的后果。目前关于（18）F 标记氟脱氧葡萄糖成像在评估血管移植物感染中的作用的文献很少，这表明该方法可能代表了这种特定临床情况下可靠的无创成像方式。PET/CT 提高了检测的特异性，从而提高了诊断的准确性。（18）F 标记氟脱氧葡萄糖 PET/CT 的精确解剖定位能够准确区分移植物和相邻软组织感染，从而进行更准确的诊断，并随后优化治疗策略。
