Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Pediatr Clin North Am. 2013 Aug;60(4):937-49. doi: 10.1016/j.pcl.2013.04.003. Epub 2013 May 11.
Infantile hemangiomas (IHs) are benign vascular tumors. Clinical history and physical examination are the most important factors for diagnosis, with most IHs having a typical presentation. Treatment is required for some IHs that cause significant cosmetic deformity or functional compromise. Propranolol is the first-line treatment of most IHs. Ongoing research is increasing our understanding of the pathophysiology of these tumors and should help to identify future potential therapeutic targets.
婴儿血管瘤(IHs)是一种良性血管肿瘤。临床病史和体格检查是诊断的最重要因素,大多数 IHs 具有典型表现。对于一些导致明显美容畸形或功能障碍的 IHs,需要进行治疗。普萘洛尔是大多数 IHs 的一线治疗药物。正在进行的研究加深了我们对这些肿瘤病理生理学的理解,应该有助于确定未来潜在的治疗靶点。