Adams Denise M, Ricci Kiersten W
Division of Hematology, Vascular Anomalies Center, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA; Oncology, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA; Division of Hematology, Hemangioma and Vascular Malformation Center, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Division of Hematology, Vascular Anomalies Center, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA; Oncology, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA; Division of Hematology, Hemangioma and Vascular Malformation Center, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Otolaryngol Clin North Am. 2018 Feb;51(1):77-87. doi: 10.1016/j.otc.2017.09.009.
Infantile hemangiomas (IHs) are benign vascular tumors of infancy most common in the region of the head and neck. Infantile hemangiomas are common; but they are extremely heterogeneous and cause a range of complications depending on their morphology, size, or location. Medical interventions for high-risk patients include topical and systemic therapies, including oral propranolol, which has revolutionized the management of IHs over the past recent years. In the following article, the authors aim to provide a review of the natural history, pathology, complications, syndromes, and medical management of infantile hemangioma.
婴儿血管瘤(IHs)是婴儿期常见的良性血管肿瘤,最常见于头颈部区域。婴儿血管瘤很常见,但它们极其异质性,并且根据其形态、大小或位置会引发一系列并发症。针对高危患者的医学干预措施包括局部和全身治疗,其中口服普萘洛尔在过去几年彻底改变了婴儿血管瘤的治疗方式。在接下来的文章中,作者旨在对婴儿血管瘤的自然病程、病理、并发症、综合征及医学管理进行综述。