Department of Urology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
BJU Int. 2013 Nov;112(7):905-8. doi: 10.1111/bju.12237. Epub 2013 Jul 26.
To determine if female partners of patients with penile cancer have more cervical lesions and neoplasia than would be expected from population-based data.
We included all consecutive patients with primary penile carcinoma in the period 2004-2010. Results of Dutch cervical cancer screening were used to consider (pre)malignant cervical lesions in female partners of patients with penile cancer.
In all, 206 women were included. Gynaecological information was available in 195 women: Papanicolaou test (PAP) smears were normal were in 129 partners, 10 smears were abnormal (5.1%, 95% confidence interval 2.5-9.2). PAP2 was found in five, PAP3a in two, PAP3b in two women and PAP4 in one woman. Colposcopy in two women with PAP3b showed cervical intraepithelial neoplasia grade 3 in both. This prevalence was not different from baseline results in the general Dutch population.
Female partners of patients with penile cancer did not show more premalignant cervical lesions than in the general population.
确定阴茎癌患者的女性伴侣是否比基于人群的数据所预期的有更多的宫颈病变和肿瘤。
我们纳入了 2004 年至 2010 年间所有连续的原发性阴茎癌患者。使用荷兰宫颈癌筛查的结果来考虑阴茎癌患者女性伴侣的（前）恶性宫颈病变。
共纳入 206 名女性。195 名女性有妇科信息：129 名伴侣的巴氏涂片正常，10 名涂片异常（5.1%，95%置信区间 2.5-9.2）。有 5 名 PAP2，2 名 PAP3a，2 名 PAP3b 和 1 名 PAP4。两名 PAP3b 女性行阴道镜检查，均显示宫颈上皮内瘤变 3 级。这一患病率与荷兰一般人群的基线结果无差异。
阴茎癌患者的女性伴侣并没有比一般人群有更多的癌前宫颈病变。
