Kumar Vishwajeet, Millar Tim, Murphy Philip N, Clough Tim
Wrightington Hospital, Hall Lane, Appley Bridge, Wigan, Lancashire WN6 9EP, United Kingdom.
Foot (Edinb). 2013 Jun-Sep;23(2-3):74-7. doi: 10.1016/j.foot.2013.06.002. Epub 2013 Jul 30.
Whilst most cases of plantar fasciitis can be settled with existing conservative treatment, a few intractable cases can be difficult to resolve. New biologic treatments have been proposed for a variety of soft tissue problems.
Evaluate the effectiveness of platelet rich plasma (PRP) in chronic cases of plantar fasciitis.
Patients with plantar fasciitis not responded to a minimum of 1 year standard conservative management were offered PRP therapy. Injections were performed in theatre as a day case. Roles-Maudsley (RM) scores, Visual Analogue Scores (VAS), AOFAS scores and 'would have injection again' were collated pre-operatively, three and six months.
Prospective data was collected of 50 heels (44 patients). At six month review, RM score improved from mean 4 to 2 (p<0.001), VAS improved from 7.7 to 4.2 (p<0.001) and AOFAS improved from 60.6 to 81.9 (p<0.001). 28 patients (64%) were very satisfied and would have the injection again. No complications were reported.
In these chronic cases, PRP produce an efficacy rate, approaching 2 out of every 3. The procedure was safe with no reported complications. The authors feel PRP may have some role in treatment, and merits further study with a prospective randomised trial.
虽然大多数足底筋膜炎病例可通过现有的保守治疗得到解决，但少数难治性病例可能难以治愈。针对各种软组织问题，已提出了新的生物治疗方法。
评估富血小板血浆（PRP）在慢性足底筋膜炎病例中的有效性。
对至少1年标准保守治疗无效的足底筋膜炎患者提供PRP治疗。在手术室作为日间手术进行注射。术前、术后3个月和6个月收集角色-莫兹利（RM）评分、视觉模拟评分（VAS）、美国足踝外科协会（AOFAS）评分以及“是否愿意再次注射”的数据。
收集了50只足跟（44例患者）的前瞻性数据。在6个月复查时，RM评分从平均4分提高到2分（p<0.001），VAS评分从7.7分提高到4.2分（p<0.001），AOFAS评分从60.6分提高到81.9分（p<0.001）。28例患者（64%）非常满意并愿意再次接受注射。未报告并发症。
在这些慢性病例中，PRP的有效率接近三分之二。该手术安全，未报告并发症。作者认为PRP可能在治疗中发挥一定作用，值得通过前瞻性随机试验进一步研究。
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